Results 21 to 30 of about 457,413 (290)
Chronic Progressive External Ophthalmoplegia Is Associated with a Novel Mutation in the Mitochondrial tRNA(Asn) Gene [PDF]
, 1994 Chronic progressive external ophthalmoplegia (CPEO) is caused by a decreased oxidative phosphorylation (OXPHOS) activity due to large-scale deletions of the mitochondrial genome in 50 % of the patients.
Kadenbach, B. +5 more
core +1 more source
Editing the Mitochondrial Genome
New England Journal of Medicine, 2020 Mending Mitochondrial Mutation For most patients with mitochondrial disorders, most of which are caused by mutations in genes in the mitochondrial genome, only symptomatic treatment is available.
Maria Falkenberg, Michio Hirano
openaire +3 more sources
Mitochondrial DNA. Part B. Resources, 2020 In this study, the complete mitochondrial genome of Sterigmatomyces hyphaenes was sequenced by the next-generation sequencing. The complete mitochondrial genome of S. hyphaenes contained 17 protein-coding genes (PCG), 2 ribosomal RNA (rRNA) genes, and 23
Maoling Tan, Qiangfeng Wang
doaj +1 more source
The complete mitochondrial genome of Xenopsylla cheopis (Siphonaptera: Pulicidae)
Mitochondrial DNA. Part B. Resources, 2022 Xenopsylla cheopis, also called oriental rat flea, is an ectoparasite as well as disease vector for murine typhus and bubonic plague. In the study, the whole mitochondrial genome of X.
Furong Wei +6 more
doaj +1 more source
The mitochondrial genome of Cavia aperea [PDF]
Mitochondrial DNA Part B, 2020 Cavia aperea is a wild guinea pig found throughout South America. The previously published mitochondrial sequence for C. aperea was highly divergent from the C. porcellus sequence and contained stop codons within open reading frames. Here we resequenced the mitochondrial genomes of C. aperea and C. porcellus.
Azizia Wahedi +3 more
openaire +6 more sources
Nature Communications, 2019 The role of mitochondrial DNA mutations in organismal fitness and lifespan have been studied in mitochondrial mutator models with varying results. Here, the authors generate a new APOBEC1 expression-based Drosophila mutator model and show that it has ...
Simonetta Andreazza +15 more
doaj +1 more source
Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability [PDF]
, 2018 R loops are nucleic acid structures comprising an DNA-RNA hybrid and a displaced single-stranded DNA. These structures may occur transiently during transcription, playing essential biological functions. However, persistent R loops may become pathological
Aguilera López, Andrés +2 more
core +1 more source
Mitochondrial DNA. Part B. Resources, 2022 Crematogaster matsumurai (Forel 1901) is an important arboreal ant species commonly found on Phyllostachys heterocycla (Carr.) in Lishui, Zhejiang, China. This study analyzed the mitochondrial genome sequence of C.
Jin-chao Wang +6 more
doaj +1 more source
Mitochondrial metagenomics: letting the genes out of the bottle [PDF]
, 2016 ‘Mitochondrial metagenomics’ (MMG) is a methodology for shotgun sequencing of total DNA from specimen mixtures and subsequent bioinformatic extraction of mitochondrial sequences.
Crampton-Platt, Alex +3 more
core +1 more source
Mitochondrial DNA. Part B. Resources, 2021 Peniophora lycii is a resupinate lichen-like species distributed all over the world. In the present study, we sequenced and assembled the complete mitochondrial genome of Peniophora lycii. The size of the mitochondrial genome of P.
Qiufen Gou, Chaoqin Ren, Cong Peng
doaj +1 more source