Results 31 to 40 of about 246,081 (272)
Ethics of modifying the mitochondrial genome [PDF]
Journal of Medical Ethics, 2010 Recent preclinical studies have shown the feasibility of specific variants of nuclear transfer to prevent mitochondrial DNA disorders. Nuclear transfer could be a valuable reproductive option for carriers of mitochondrial mutations. A clinical application of nuclear transfer, however, would entail germ-line modification, more specifically a germ-line ...
Bredenoord, A L +3 more
openaire +5 more sources
Mitochondrial DNA. Part B. Resources, 2021 Peniophora lycii is a resupinate lichen-like species distributed all over the world. In the present study, we sequenced and assembled the complete mitochondrial genome of Peniophora lycii. The size of the mitochondrial genome of P.
Qiufen Gou, Chaoqin Ren, Cong Peng
doaj +1 more source
Mitochondrial DNA. Part B. Resources, 2020 Cervus canadensis (Erxleben, 1777) has been used as a model species of Chronic Wasting Disease (CWD). We completed the mitochondrial genome of C. canadensis, susceptible to the CWD.
Hyo-Jin Kim +6 more
doaj +1 more source
The Oxytricha trifallax Mitochondrial Genome [PDF]
Genome Biology and Evolution, 2011 The Oxytricha trifallax mitochondrial genome contains the largest sequenced ciliate mitochondrial chromosome (~70 kb) plus a ~5-kb linear plasmid bearing mitochondrial telomeres. We identify two new ciliate split genes (rps3 and nad2) as well as four new mitochondrial genes (ribosomal small subunit protein genes: rps- 2, 7, 8, 10), previously ...
Heather Stiles +11 more
openaire +4 more sources
Transformation of the mitochondrial genome
The International Journal of Developmental Biology, 2013 Although mitochondrial transformation is highly desirable in mammals and plants, it is only possible in two unicellular organisms, the budding yeast Saccharomyces cerevisiae and the unicellular green alga Chlamydomonas reinhardtii. Here, we give an overview of the attempts made to transform mitochondria of mammals and plants and the possible reasons ...
Véronique Larosa, Claire Remacle
openaire +4 more sources
Origin of minicircular mitochondrial genomes in red algae
Nature Communications, 2023 Eukaryotic organelle genomes are generally of conserved size and gene content within phylogenetic groups. However, significant variation in genome structure may occur.
Yongsung Lee +9 more
doaj +1 more source
Population genomics of the Wolbachia endosymbiont in Drosophila melanogaster [PDF]
Richardson MF, Weinert LA, Welch JJ, Linheiro RS, Magwire MM, et
al. (2012) Population Genomics of the Wolbachia Endosymbiont in Drosophila
melanogaster. PLoS Genet 8(12): e1003129, 2012 Wolbachia are maternally-inherited symbiotic bacteria commonly found in arthropods, which are able to manipulate the reproduction of their host in order to maximise their transmission. Here we use whole genome resequencing data from 290 lines of Drosophila melanogaster from North America, Europe and Africa to predict Wolbachia infection status ...
arxiv +1 more source
Mitochondrial heterogeneity [PDF]
, 2018 Cell-to-cell heterogeneity drives a range of (patho)physiologically important phenomena, such as cell fate and chemotherapeutic resistance. The role of metabolism, and particularly mitochondria, is increasingly being recognised as an important explanatory factor in cell-to-cell heterogeneity.
arxiv +1 more source
Encounter networks from collective mitochondrial dynamics support the emergence of effective mtDNA genomes in plant cells [PDF]
arXiv, 2021 Mitochondria in plant cells form strikingly dynamic populations of largely individual organelles. Each mitochondrion contains on average less than a full copy of the mitochondrial DNA (mtDNA) genome. Here, we asked whether mitochondrial dynamics may allow individual mitochondria to `collect' a full copy of the mtDNA genome over time, by facilitating ...
arxiv