Results 51 to 60 of about 576,544 (290)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Are we there yet? : reliably estimating the completeness of plant genome sequences [PDF]

, 2016
Genome sequencing is becoming cheaper and faster thanks to the introduction of next-generation sequencing techniques. Dozens of new plant genome sequences have been released in recent years, ranging from small to gigantic repeat-rich or polyploid genomes.
Ruttink, Tom, Vandepoele, Klaas, Veeckman, Elisabeth   +2 more
core   +3 more sources

Comparative Genomics of Plant Chromosomes [PDF]

The Plant Cell, 2000
Comparative genomics, the study of similarities and differences in structure and function of the hereditary information in different taxa, uses molecular tools to investigate notions that far preceded the discovery that DNA was the hereditary molecule.
Christine G. Elsik, Xavier Draye, Reiguang Ming, John E. Bowers, Mark D. Burow, Mark D. Burow, Tien-Hung Lan, Chun-Xiao Jiang, Robert J. Wright, C. S. Katsar, Andrew H. Paterson, Yann-Rong Lin   +11 more
openaire   +3 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

SUPER STARCHY1/ONAC025 participates in rice grain filling

Plant Direct, 2020
NAC transcription factors (TFs) are known for their role in development and stress. This article attempts to functionally validate the role of rice SS1/ ONAC025 (LOC_Os11g31330) during seed development.
Iny Elizebeth Mathew, Richa Priyadarshini, Arunima Mahto, Priya Jaiswal, Swarup K. Parida, Pinky Agarwal   +5 more
doaj   +1 more source

Molecular and expression analysis indicate the role of CBL interacting protein kinases (CIPKs) in abiotic stress signaling and development in chickpea

Scientific Reports, 2022
Calcineurin B-like proteins (CBL)-interacting protein kinases (CIPKs) regulate the developmental processes, hormone signal transduction and stress responses in plants. Although the genome sequence of chickpea is available, information related to the CIPK
Nikita Poddar, Deepika Deepika, Pragya Chitkara, Amarjeet Singh, Shailesh Kumar   +4 more
doaj   +1 more source

Nicotinic Acid Catabolism Modulates Bacterial Mycophagy in Burkholderia gladioli Strain NGJ1

Microbiology Spectrum, 2023
Burkholderia gladioli strain NGJ1 exhibits mycophagous activity on a broad range of fungi, including Rhizoctonia solani, a devastating plant pathogen. Here, we demonstrate that the nicotinic acid (NA) catabolic pathway in NGJ1 is required for mycophagy ...
Joyati Das, Rahul Kumar, Sunil Kumar Yadav, Gopaljee Jha   +3 more
doaj   +1 more source

Advances in Genetical Genomics of Plants [PDF]

Current Genomics, 2009
Natural variation provides a valuable resource to study the genetic regulation of quantitative traits. In quantitative trait locus (QTL) analyses this variation, captured in segregating mapping populations, is used to identify the genomic regions affecting these traits.
Joosen, R.V.L., Ligterink, W., Hilhorst, H.W.M., Keurentjes, J.J.B.   +3 more
openaire   +3 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Deciphering the genome structure and paleohistory of _Theobroma cacao_ [PDF]

, 2010
We sequenced and assembled the genome of _Theobroma cacao_, an economically important tropical fruit tree crop that is the source of chocolate. The assembly corresponds to 76% of the estimated genome size and contains almost all previously described ...
Angé, Ange Marie Risterucci, Anne Dievart, Auré, Bertrand Pitollat, Christopher Viot, Claire Lanaud, Cristian Chaparro, Dave Kudrna, Didier Clement, Diogenes Infante, Dominique Brunel, Emmanuel Guiderdoni, Erika Sallet, Florent Murat, Francis Quetier, Francois Sabot, Gaetan Droc, Ismael Kebe, Jean Marc Aury, Jerome Gouzy, Jerome Salse, Jetty Siva S. Ammiraju, John E. Carlson, Jose Fernandes Barbosa-Neto, Joseph Moroh Akaza, Julie Poulain, Karina Gramacho, Laura Gelley, Maguy Rodier-Goud, Manuel Ruiz, Mark Guiltinan, Mathias Tahi, Mathilde Allegre, Melissa Kramer, Michael Abrouk, Michael Axtell, Michel Boccara, Mickael Bourge, Olivier Fouet, Olivier Panaud, Patrick Wincker, Pierre Costet, Rod Wing, Ronan Rivalan, Schiex T., Siela Maximova, Spencer Brown, Stephan C. Schuster, Stephanie Sidibe-Bocs, Thierry Legavre, Valentin Guignon, W. Richard McCombie, Wolfgang Golser, Xavier Argout, Xavier Sabau, Xiang Song, Yolande Roguet, Yufan Zhang, Zhaorong Ma, Zi Sh   +60 more
core   +2 more sources