Results 141 to 150 of about 2,630,320 (343)
Vgas: A Viral Genome Annotation System
Frontiers in Microbiology, 2019 The in-depth study of viral genomes is of great help in many aspects, especially in the treatment of human diseases caused by viral infections. With the rapid accumulation of viral sequencing data, improved, or alternative gene-finding systems have ...
Kai-Yue Zhang +5 more
doaj +1 more source
vir2vec: A Viral Genome-Wide Viral Embedding
Abstract Genomic language models (gLMs) have recently emerged as powerful numerical surrogates for DNA, but existing architectures are largely focused on human DNA or trained on limited viral references, and no dedicated benchmark currently exists for viral genome understanding.
Simone Rancati +12 more
openaire +2 more sources
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Host ZCCHC3 blocks HIV-1 infection and production through a dual mechanism
iScienceSummary: Most mammalian cells prevent viral infection and proliferation by expressing various restriction factors and sensors that activate the immune system.
Binbin Yi +9 more
doaj +1 more source
Isolation of poliovirus 2C mutants defective in viral RNA synthesis [PDF]
, 1988 Two poliovirus mutants were isolated that contain an oligonucleotide linker insertion in the 2C-coding region of the viral genome. One, 2C-31, has a strongly temperature-sensitive phenotype and the other, 2C-32, forms small plaques on HeLa cell ...
Baltimore, David, Li, Jing-Po
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
viruSITE—integrated database for viral genomics
Database, 2016 Viruses are the most abundant biological entities and the reservoir of most of the genetic diversity in the Earth's biosphere. Viral genomes are very diverse, generally short in length and compared to other organisms carry only few genes. viruSITE is a novel database which brings together high-value information compiled from various resources. viruSITE
Matej Stano, Gabor Beke, Lubos Klucar
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Endogenous Dionyvirus sequences are widespread in plant genomes [PDF]
, 2011 Endogenous sequences from members of the Caulimoviridae and Geminiviridae families have been identified in the genome of several plant species [1, 2].
Choisne, Nathalie +7 more
core
Arthritis Care &Research, EarlyView.Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch +6 more
wiley +1 more source