Results 211 to 220 of about 669,373 (262)

Estimates of HIV-1 within-host recombination rates across the whole genome. [PDF]

Virus Evol
Longley H, Bonsall D, Herbeck J, MacIntyre-Cockett G, Chaudron SE, Thomson L, Grayson N, Mujugira A, PANGEA consortium, Fraser C, Lingappa J, Lythgoe K.   +11 more
europepmc   +1 more source

TBC1D22B Regulates ER‐to‐Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast Cancer

Advanced Science, EarlyView.
TBC1D22B, a Golgi‐localized RabGAP linked to poor prognosis in breast cancer, inhibits ER‐to‐Golgi transport via RAB1B inactivation. This disrupts secretion, drives oncogenic transcriptional reprogramming, and promotes tumor growth. These findings indicate that TBC1D22B connects membrane trafficking to transcriptional control and cancer progression ...
Flavia Martino, Mariadomenica Lupi, Alessandra Murabito, Fabio Bedin, Giulia Villari, Linda Andreoli, Stefano Freddi, Bronislava Matoskova, Rosa Pennisi, Stella Fontana, Amir Fardin, Gaelle Boncompain, Franck Perez, Federico Bussolino, Alessandro Cuomo, Sara Sigismund, Letizia Lanzetti   +16 more
wiley   +1 more source

Validation of diverse and previously untraceable Sendai virus copyback viral genomes by direct RNA sequencing. [PDF]

J Virol
Pye SE, Achouri E, Yang Y, Musa A, López CB.   +4 more
europepmc   +1 more source

Single‐Cell Transcriptome Analysis Reveals That Hmga2 Regulates Neuroinflammation and Retinal Function by Modulating Müller Cell Autophagy Through PI3K/AKT Signaling Following MCAO‐Induced Retinal Ischemia

Advanced Science, EarlyView.
Employing snRNA‐seq post‐MCAO‐induced retinal ischemia (RI), this study revealed a novel Hmga2‐high Müller cell subpopulation. Hmga2 knockout alleviated neuroinflammation and RI symptoms, potentially by binding PI3K and regulating Müller cell autophagy.
Weihao Lv, Juzheng Yuan, Zhe Ruan, Ya‐nan Dou, Hongchen Zhang, Xiaowei Fei, Leiying Chen, Zehan Zhang, Kai Yang, Xiuquan Wu, Zhou Fei, Fei Fei   +11 more
wiley   +1 more source

Whole-Genome Sequencing and Structure Study of Three Biting-Insect-Associated Viruses (<i>Yunnan Orbivirus</i>, Guangxi Orbivirus, and Yongshan Totivirus) Isolated in Yunnan, China. [PDF]

Adv Virol
Li Z, Duan Y, Zhu J, Li L.
europepmc   +1 more source

Whole-Genome sequencing of Chikungunya Virus (CHIKV) from Pakistan: Detection of the East/Central/South African (ECSA) genotype during the 2024 outbreak in Mansehra. [PDF]

PLoS One
Umair M, Yasir M, Jamal Z, Hakim R, Saeed SY, Salman M, Iqbal A, Khan MQ, Khanzada F, Javed Y.   +9 more
europepmc   +1 more source

Development of the coronavirus reverse genetic system: Core technology for pathogenesis mechanisms research and vaccine/drug development. [PDF]

Virulence
Zhang Y, Hou R, Wei Z, Yuan J, Zu S.
europepmc   +1 more source

Integrating metagenomics and cultivation unveils oral phage diversity and potential impact on hosts. [PDF]

NPJ Biofilms Microbiomes
Jie Z, Liang H, Meng Y, Zhang J, Zhang T, Li W, Lin X, Hu T, Han M, Liang W, Ju Y, Tong X, Jin X, Xu X, Zhang W, Wang J, Yang H, Kristiansen K, Xiao L, Zou Y.   +19 more
europepmc   +1 more source

Applications of CRISPR-Cas-Based Genome Editing Approaches Against Human Cytomegalovirus Infection. [PDF]

Biomedicines
Zhang A, Zhang I, Liu F.
europepmc   +1 more source