Results 221 to 230 of about 3,091,688 (344)
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
Nature Genetics, 2010 E. Stahl, S. Raychaudhuri, E. Remmers, G. Xie, S. Eyre, Brian Thomson, Yonghong Li, F. Kurreeman, A. Zhernakova, A. Hinks, C. Guiducci, Robert Chen, L. Alfredsson, C. Amos, K. Ardlie, A. Barton, J. Bowes, E. Brouwer, N. Burtt, J. Catanese, J. Coblyn, M. Coenen, K. Costenbader, L. Criswell, J. Crusius, J. Cui, P. D. Bakker, P. D. Jager, B. Ding, P. Emery, E. Flynn, Pille Harrison, L. Hocking, T. Huizinga, D. Kastner, X. Ke, Annette Lee, Xiangdong Liu, Paul Martin, A. Morgan, L. Padyukov, M. Posthumus, T. Radstake, D. Reid, Mark Seielstad, M. Seldin, N. Shadick, S. Steer, P. Tak, W. Thomson, A. Mil, I. Horst-Bruinsma, C. E. Schoot, P. Riel, M. Weinblatt, A. Wilson, G. Wolbink, Bryan Paul Wordsworth, C. Wijmenga, E. Karlson, R. Toes, N. Vries, A. Begovich, Jane Worthington, K. Siminovitch, P. Gregersen, L. Klareskog, R. Plenge +67 moresemanticscholar +1 more sourceStrength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra +3 morewiley +1 more sourceMulti-ethnic genome-wide association study for atrial fibrillation
Nature Genetics, 2018 C. Roselli, M. Chaffin, L. Weng, S. Aeschbacher, G. Ahlberg, Christine M. Albert, P. Almgren, Á. Alonso, Christopher D. Anderson, Krishna G. Aragam, D. Arking, J. Barnard, T. Bartz, Emelia J. Benjamin, Nathan A. Bihlmeyer, J. Bis, Heather L. Bloom, E. Boerwinkle, Erwin Bottinger, J. Brody, H. Calkins, A. Campbell, Thomas P. Cappola, John Carlquist, D. Chasman, Lin Y Chen, Yii-DerIda Chen, Eue-Keun Choi, Seung Hoan Choi, IE Christophersen, M. Chung, John W. Cole, D. Conen, J. Cook, H. Crijns, Michael J. Cutler, S. Damrauer, Brian R. Daniels, D. Darbar, G. Delgado, Josh C. Denny, M. Dichgans, M. Dörr, E. Dudink, Samuel C. Dudley, Nada Esa, T. Esko, M. Eskola, D. Fatkin, S. Felix, I. Ford, Oscar H. Franco, B. Geelhoed, R. Grewal, V. Gudnason, Xiuqing Guo, N. Gupta, S. Gustafsson, Rebecca Gutmann, A. Hamsten, Tamara B. Harris, C. Hayward, S. Heckbert, J. Hernesniemi, L. Hocking, A. Hofman, A. Horimoto, Jie Huang, Paul L. Huang, J. Huffman, E. Ingelsson, E. G. Ipek, K. Ito, J. Jiménez-Conde, Renee Johnson, J. Jukema, S. Kääb, M. Kähönen, Y. Kamatani, J P Kane, A. Kastrati, S. Kathiresan, P. Katschnig-Winter, M. Kavousi, T. Kessler, B. Kietselaer, P. Kirchhof, M. Kleber, Stacey Knight, J. E. Krieger, M. Kubo, L. Launer, J. Laurikka, T. Lehtimäki, K. Leineweber, R. N. Lemaitre, Man Li, Hong Euy Lim, Henry J. Lin, Honghuang Lin, L. Lind, Cecilia M. Lindgren, M. Lokki, B. London, R. Loos, Siew-Kee Low, Yingchang Lu, L. Lyytikäinen, Peter W. Macfarlane, P. Magnusson, A. Mahajan, R. Malik, Alfredo J. Mansur, Gregory M. Marcus, L. Margolin, Kenneth B. Margulies, Winfried März, David D. McManus, O. Melander, S. Mohanty, Jay A. Montgomery, Michael P. Morley, Andrew P. Morris, M. Müller-Nurasyid, A. Natale, S. Nazarian, Benjamin Neumann, C. Newton‐Cheh, M. Niemeijer, K. Nikus, P. Nilsson, R. Noordam, Heidi Oellers, M. S. Olesen, M. Orho-Melander, S. Padmanabhan, H. Pak, Guillaume Paré, N. Pedersen, J. Pera, A. Pereira, D. Porteous, B. Psaty, Sara L. Pulit, C. Pullinger, Daniel J. Rader, L. Refsgaard, M. Ribasés, P. Ridker, M. Rienstra, L. Risch, Dan M. Roden, J. Rosand, Michael A. Rosenberg, Natalia S. Rost, Jerome I. Rotter, S. Saba, R. Sandhu, R. Schnabel, K. Schramm, H. Schunkert, Claudia Schurman, Stuart A. Scott, I. Seppälä, C. Shaffer, Svati H. Shah, Alaa A. Shalaby, J. Shim, M. B. Shoemaker, J. Siland, J. Sinisalo, Moritz F. Sinner, A. Słowik, Albert V. Smith, Blair H. Smith, J. G. Smith, Jonathan D. Smith, Nicholas L. Smith, E. Soliman, N. Sotoodehnia, B. Stricker, A. Sun, Han Sun, J. H. Svendsen, Toshihiro Tanaka, K. Tanriverdi, K. Taylor, M. Teder-Laving, A. Teumer, S. Thériault, S. Trompet, N. Tucker, A. Tveit, A. Uitterlinden, P. van der Harst, I. V. Van Gelder, D. V. Van Wagoner, N. Verweij, E. Vlachopoulou, U. Völker, Biqi Wang, P. Weeke, B. Weijs, R. Weiss, S. Weiss, Q. Wells, K. Wiggins, Jorge A. Wong, D. Woo, B. Worrall, Pil‐Sung Yang, Jie Yao, Z. Yoneda, T. Zeller, Lingyao Zeng, S. Lubitz, K. Lunetta, P. Ellinor +217 moresemanticscholar +1 more sourceGenome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer
, 2014 Þórunn Rafnar, Patrick Sulem, Guðmar Þorleifsson, Sita H. Vermeulen, Hannes Helgason, Jona Saemundsdottir, Sigurjón A. Guðjónsson, Ásgeir Sigurðsson, Simon Stacey, Jūlı́us Guðmundsson, Hrefna Johannsdottir, Kristín Alexíusdóttir, Vigdís Pétursdóttir, Sigfús Nikulásson, Guðmundur Geirsson, Þorvaldur Jónsson, Katja K.H. Aben, Anne J. Grotenhuis, Gerald W. Verhaegh, Aleksandra M. Dudek, J.A. Witjes, Antoine G. van der Heijden, Alina Vrieling, Tessel E. Galesloot, Ana De Juan, Angeles Panadero, Fernando Rivera, Carolyn D. Hurst, D. Timothy Bishop, Sei Chung Sak, Ananya Choudhury, Mark Teo, Cecilia Arici, Angela Carta, Elena Toninelli, Petra de Verdier, Péter Rudnai, Eugen Gurzău, Kvetoslava Koppová, Kirstin A. van der Keur, Irene Lurkin, Mieke Goossens, Eliane Kellen, Simonetta Guarrera, Alessia Russo, Rossana Critelli, Carlotta Sacerdote, Paolo Vineis, Clémentine Krucker, Maurice P. Zeegers, Holger Gerullis, Д Ю Овсянников, Frank Volkert, Jan G. Hengstler, Silvia Selinski, Ólafur Þ. Magnússon, Gísli Másson, Augustine Kong, Daníel F. Guðbjartsson, Annika Lindblom, Ellen C. Zwarthoff, Stefano Porru, Klaus Golka, Frank Buntinx, Giuseppe Matullo, Rajiv Kumar, José Mayordomo, D. Gunnar Steineck, Anne E. Kiltie, Eiríkur Jónsson, François Radvanyi, Margaret A. Knowles, Unnur Þorsteinsdóttir, Lambertus A. Kiemeney, Kāri Stefánsson +74 moreopenalex +2 more sourcesGenome-wide association study of REM sleep behavior disorder in Parkinson's disease. [PDF]
NPJ Parkinsons DisSosero YL, Heilbron K, Fontanillas P, Norcliffe-Kaufmann L, Yu E, Rudakou U, Ruskey JA, Freeman K, Asayesh F, Brolin KA, Swanberg M, Morris HR, Wu L, Real R, Pihlstrøm L, Tan M, Gasser T, Brockmann K, Liu H, Hu MTM, Grosset DG, Lewis SJG, Kwok JB, Pastor P, Alvarez I, Skorvanek M, Lackova A, Ostrozovicova M, Rizig M, 23andMe Research Team, International Parkinson’s Disease Genomics Consortium, Krohn L, Gan-Or Z. +32 moreeuropepmc +1 more sourceTranscriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal +16 morewiley +1 more sourceGenome-wide association study of susceptibility to acute respiratory distress syndrome. [PDF]
EBioMedicineGuillen-Guio B, Suarez-Pajes E, Tosco-Herrera E, Hernandez-Beeftink T, Lorenzo-Salazar JM, Chang D, González-Montelongo R, Rubio-Rodríguez LA, Leavy OC, Allen RJ, Corrales A, Cruz R, Bardají-Carrillo M, Carracedo A, Tamayo E, Kerchberger VE, Ware LB, Yaspan BL, Scholz M, Scherag A, Villar J, Wain LV, Flores C. +22 moreeuropepmc +1 more sourceMonitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien +35 morewiley +1 more source
