Results 161 to 170 of about 754,015 (260)

Genome-wide analysis reveals pathways important for the development and maturation of excitatory synaptic connections to GABAergic neurons. [PDF]

G3 (Bethesda)
Oliver DB, Ramachandran S, Biswas K, Bénard CY, Doitsidou M, McKillop H, Genao N, Lemons ML, Francis MM.   +8 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

TEGS-CN: A Statistical Method for Pathway Analysis of Genome-wide Copy Number Profile

Cancer Informatics, 2014
Yen-Tsung Huang, Thomas Hsu, David C. Christiani   +2 more
doaj  

Genome-wide analysis of cardiac ventricular phenotypes reveals novel loci and therapeutic targets for heart failure. [PDF]

Nat Commun
Nicholls HL, Vargas JD, Sanghvi MM, Ahn HS, Chahal CAA, Khanji MY, Petersen SE, Munroe PB, Aung N.   +8 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Genome-Wide Analysis of Tomato SlCCD Genes and the Role of SlCCD11 in Enhancing Salt Tolerance. [PDF]

Plants (Basel)
An C, Liu Z, Liu M, Li Q, Wang Q, Cao M, Geng X, Wang C.   +7 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Key Genomic Regions of Rice Cultivar GuiHeFeng and Its Derivatives Revealed by Genome-Wide Analysis. [PDF]

Plants (Basel)
Chen YZ, Hao XY, Zhang YX, Ma ZF, Liu C, Zhou XL, Wei MY, Qin BX, Yan Y, Huang DH.   +9 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Genome-Wide Analysis of NAC Transcription Factor Genes in the Invasive Weed <i>Mikania micrantha</i> Provides Insights into Potential Control Strategies. [PDF]

Biology (Basel)
Song W, Ding Y, Yang L, Li W, Zhao N.
europepmc   +1 more source