Results 271 to 280 of about 189,144 (345)

Genomic Structural Equation Modeling Reveals Cardiovascular-Kidney-Metabolic Syndrome Genetic Architecture. [PDF]

J Diabetes
Lu C, Li L, Chen J, Chang R, Dong H.
europepmc   +1 more source

New perspectives on VEGF signalling in Alzheimer's disease

Brain Pathology, EarlyView.
Emery et al. bring together findings from recent multi‐omic studies, including single‐cell mRNA analysis of human post‐mortem brain tissue, and proteomic analysis of matched CSF and blood samples in large clinical studies. The authors present evidence of the involvement of altered VEGF signalling in vascular and immune dysfunction and neurodegeneration
Cherelle E. G. Emery, Seth Love, J. Scott Miners   +2 more
wiley   +1 more source

Impact of control selection strategies on GWAS results: a study of prostate cancer in the UK Biobank. [PDF]

Brief Bioinform
Lu J, Thygesen JH, Beaumont RN, Weedon MN, Green HD.   +4 more
europepmc   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

An evaluation of age-varying genetic effects underlying body-mass index and blood pressure in the UK Biobank. [PDF]

PLoS Genet
Leyden GM, Pagoni P, Power GM, Carslake D, Richardson TG, Tilling K, Hemani G, Davey Smith G, Sanderson E.   +8 more
europepmc   +1 more source

Genetic study identifies novel genes in developmental dysplasia of the hip. [PDF]

Bone Res
Yoshino S, Chen S, Yamaguchi R, Kurakazu T, Hatzikotoulas K, Koike Y, Inoue D, Kohno Y, Sasaki K, Choe H, Baba S, Hara T, Ito J, Okuzu Y, Shiomoto K, Nakamura T, Koyano G, Shimizu T, Kinoshita K, Takahashi E, Utsunomiya T, Hara D, Sato T, Kawahara S, Kaneuji A, Yamamoto T, Takahashi D, Jinno T, Kawano T, Goto K, Takagi M, Mawatari T, Inaba Y, Nakamura T, Kabata T, Hamai S, Motomura G, Southam L, Wilkinson JM, Zeggini E, Ikegawa S, Nakashima Y, Terao C.   +42 more
europepmc   +1 more source

Genome-wide association studies (GWAS) for resistance to Meloidogyne graminicola in an association panel of Oryza rufipogon

Sekhon Anupam, Kaur Dhillon Narpinderjeet, Bhatia Dharminder, Singh Buttar Harwinder   +3 more
openalex   +2 more sources

Cardiometabolic Risk in First Degree Relatives of Women With Polycystic Ovary Syndrome (PCOS)

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a common multisystem disorder with reproductive, cardiometabolic and psychological implications. Genetic factors play a role in the pathogenesis of PCOS. We sought to investigate the cardiometabolic health of first degree relatives (FDR) of women with PCOS.
Su Jen Chua, Xinyi Wu, Tahani Al Kindi, Bulent O. Yildiz, Aya Mousa, Loyal Pattuwage, Helena Teede, Anju E. Joham, Chau Thien Tay   +8 more
wiley   +1 more source

A Pooled Blood Genome-Wide Association Study of Hypertension in Sindhi Families: Results from the DISFIN Study. [PDF]

Genes (Basel)
Kanaskar S, Patel AA, Jaisinghani MT, Pipal KV, Kanaskar M, Mamtani M, Kulkarni H.   +6 more
europepmc   +1 more source

The development of type 2 diabetes amongst sibling pairs in the South‐South region of Nigeria: The effect of genetics, environment and lifestyle

Diabetic Medicine, EarlyView.
Abstract Introduction Type 2 diabetes is a complex condition with a multifactorial pathogenesis. The pathogenesis is considered to be polygenic due to complex interactions between genetic/epigenetic and environmental factors. The aim of this study is to determine the genetic, environmental and lifestyle factors associated with the development of type 2
Sunny Chinenye, Ibi Erekosima, Adrian H. Heald, Gesiye Bozimo, Simon G. Anderson, Samuel Seidu, Kariba Akhidue, Adaeze Ugwu, Chioma Unachukwu, Ibitrokoemi Korubo, Kingsley Chukwuemeka Patrick‐Iwuanyanwu, Victoria Gomba, Uwoma Batubo, Victoria Akanatei, Victor Ken‐Uba, Iyeopu Siminialayi, Sokiprim Akoko, Justin Ideozu, Hamilton Opurum   +18 more
wiley   +1 more source