Results 281 to 290 of about 189,144 (345)

Polygenic Risk Score Predicts Prostate Cancer Risk Independent of Type 2 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Type 2 diabetes mellitus (T2DM) has been inversely associated with prostate cancer (PrCa) risk. However, it remains unclear whether a polygenic risk score (PRS) for PrCa can effectively stratify risk among men with T2DM. The primary objective of this study was to assess whether a PrCa PRS predicts PrCa risk independently of T2DM status ...
Guk Jin Lee, Sang‐Hyuk Jung, Jonghyun Lee, Ki Won Moon, Penn Medicine Biobank, Daniel J. Rader, Marylyn D. Ritchie, JoEllen Weaver, Nawar Naseer, Giorgio Sirugo, Afiya Poindexter, Yi‐An Ko, Kyle P. Nerz, Meghan Livingstone, Fred Vadivieso, Stephanie DerOhannessian, Teo Tran, Julia Stephanowski, Salma Santos, Ned Haubein, Joseph Dunn, Colleen Morse Kripke, Marjorie Risman, Renae Judy, Colin Wollack, Anurag Verma, Shefali S. Verma, Scott Damrauer, Yuki Bradford, Scott Dudek, Theodore Drivas, Jae‐Seung Yun, Dokyoon Kim   +32 more
wiley   +1 more source

A decade of discovery: Leveraging genomic data in the ABCD study to illuminate adolescent neurodevelopment. [PDF]

Dev Cogn Neurosci
Hernandez LM, Loughnan R, Cheng W, Zhang L, Fan CC, Agrawal A, ABCD Genetics Workgroup.   +6 more
europepmc   +1 more source

Genome-wide association studies (GWAS) of IOP, Height and Refractive Error

Jeremy A. Guggenheim, Xi He
openalex   +1 more source

Proteomic Profiling of Plasma to Uncover Novel Intervention Targets and Prognostic Biomarkers for Chronic Liver Diseases

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The burden of chronic liver disease (CLD) is increasing. This study aims to identify protein markers for CLD and its progression, and develop a protein‐based risk prediction model. Materials and Methods We used proteome‐wide Mendelian randomization (MR), Bayesian colocalization and summary‐data‐based MR with proteomic data from deCODE ...
Xinxuan Li, Jing Sun, Jianhui Zhao, Fangyuan Jiang, Meng Zhang, Hao Wu, Shuai Yuan, Xue Li, Juan Lu, Christos S. Mantzoros   +9 more
wiley   +1 more source

Genomic, phenomic and geographic associations of leukocyte telomere length in the United States. [PDF]

Nat Genet
Nakao T, Koyama S, Truong B, Uddin MM, Misra A, Patel AP, Bhatnagar A, Viscosi V, Vlasschaert C, Bick AG, Nelson CP, Codd V, Samani NJ, Hornsby W, Ellinor PT, Natarajan P.   +15 more
europepmc   +1 more source

Manhattan plots and QQ plots for different genome-wide association study (GWAS) models.

Yurim Kim (17146478), Myoung-Goo Choi (21222093), Myoung Hui Lee (11788694), Chuloh Cho (484815), Jun Yong Choi (290863), Suk-Jin Kim (21222096), Chon-Sik Kang (4236202), Chul Soo Park (8108045), Ki-Chang Jang (18557676), Youngjun Mo (5880638), Changhyun Choi (4763991)   +10 more
openalex   +1 more source

Genetic architecture of plasma pTau217 and related biomarkers in Alzheimer's disease via genome-wide association studies. [PDF]

Alzheimers Dement
Kim JP, Song M, Cho M, Lee H, Jung SH, Lim S, Kim C, Jang B, Shin D, Kang H, Yim S, Jang H, Kim BH, Kim HJ, Na DL, An JY, Zetterberg H, Blennow K, Gonzalez-Ortiz F, Ashton NJ, Day TA, Seo SW, Won HH.   +22 more
europepmc   +1 more source

A rapid review of genetic association studies of parent-of-origin effects and fetal growth. [PDF]

Mol Cell Pediatr
Kang EJW, Dewan AT.
europepmc   +1 more source

Dissecting the Genetic Basis of Low Back Pain Independent of BMI Through Genomic Structural Equation Modeling. [PDF]

J Pain Res
Huo L, Tan L, Wang F, Sun J, Niu Y, Jiang Y, Wu M, Shi J, Hao Y, Wang J, Huang S, Chen Z.   +11 more
europepmc   +1 more source

Genome association of carbohydrate metabolites provides new insights toward functional breeding in coffee. [PDF]

Plant Genome
Tavares Flores E, Spicer RL, Souza EMR, Ferrão MAG, Senra JFB, Azevedo C, Munoz PR, Tieman D, Voiniciuc C, Ferrão LFV.   +9 more
europepmc   +1 more source