Results 111 to 120 of about 2,680,695 (316)

Pantoea stewartii subsp. stewartii an Inter-Laboratory Comparative Study of Molecular Tests and Comparative Genome Analysis of Italian Strains

open access: yesPlants
Pantoea stewartii subsp. stewartii (Pss) is a Gram-negative bacterium causing Stewart wilt, a severe disease in maize. Native to North America, it has spread globally through the maize seed trade. Resistant maize varieties and insecticides are crucial to
Valeria Scala   +23 more
doaj   +1 more source

The Signal in the Genomes

open access: yesPLoS Computational Biology, 2006
Nostra culpa. Not only did we foist a hastily conceived and incorrectly executed simulation on an overworked RECOMB conference program committee, but worse—nostra maxima culpa—we obliged a team of high-powered researchers to clean up after us! It was never our intention to introduce an alternative way of constructing synteny blocks; the so-called ST ...
openaire   +3 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Tetraploid Wheat Germplasm Diversity Scan based on the Durum Wheat Genome Assembly

open access: yes, 2018
The genome of modern durum wheat (DW) cultivar Svevo has been assembled based on a combination of whole genome shotgun sequencing (270X), NRGene deNovoMagic assembler, high-resolution genetic mapping obtained from the cross between Svevo DW and Zavitan ...
Raj K Pasam   +18 more
core   +1 more source

Genome De Novo (WGS) Sequence Resource of the Lasiodiplodia theobromae Bot-2018-LT45 Isolate Causing Dieback in Apple

open access: yesInternational Journal of Plant Biology
Lasiodiplodia theobromae is a pathogenic fungus associated with tropical perennial fruit plants worldwide. In apple trees, L. theobromae causes dieback and canker, a disease that affects the architecture of the wood producing the progressive death of ...
Adrián V. Valdez-Tenezaca   +7 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Help in Accessing Human Genome Information

open access: yes, 2000
lette
International Human Genome Sequencing Consortium
core  

DURUM WHEAT GENOME SCAN REVEALED TEN-THOUSAND YEAR EMPIRICAL SELECTION AND BREEDING EFFECTS

open access: yes, 2017
The durum wheat Svevo genome has bee n assembled to nearly completeness, more than 66k high confidence genes plus 8.4 Gb (82%) of repetitive elements were annotated and more than 928k sequence based molecular markers were projected onto the genome. By
L. Cattivelli   +2 more
core   +1 more source

Chromosome-level draft genome assembly of Hypomesus nipponensis reveals transposable element expansion reshaping the genome structure

open access: yesFrontiers in Genetics
Hypomesus nipponensis a commercially valuable fish within the Osmeriformes order, is naturally found in northeastern Asia and has been extensively introduced for commercial purposes across eastern Asia.
Chenzhao Zhu   +5 more
doaj   +1 more source

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