Results 121 to 130 of about 2,754,601 (316)

Genome De Novo (WGS) Sequence Resource of the Lasiodiplodia theobromae Bot-2018-LT45 Isolate Causing Dieback in Apple

International Journal of Plant Biology
Lasiodiplodia theobromae is a pathogenic fungus associated with tropical perennial fruit plants worldwide. In apple trees, L. theobromae causes dieback and canker, a disease that affects the architecture of the wood producing the progressive death of ...
Adrián V. Valdez-Tenezaca, Sergio A. Hernández Covarrubias, Alexis G. Murillo Carrasco, Matías I. Guerra Peñalosa, Jean F. Castro Figueroa, M. Ernesto Delgado Fernández, José A. Corona-Gómez, Gonzalo A. Díaz Ulloa   +7 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Genome-wide distributed SNPs identified in the Black Bengal goat versus the Yunnan Black goat genome

, 2019
Genome-wide SNPs were detected by aligning whole genome sequence of Black Bengal goat with Yunnan Black goat genome (GCA_000317765.2)
Gautam Kumar Deb (6325275), Md Panir Choudhury (6325276), Md Shamsul Alam Bhuiyan (6325268), Md Bazlur Rahman Mollah (4861135), Md Abdul Jalil (6325273), MAM Yahia Khandoker (6325271), Nure Hasni Desha (6325278)   +6 more
core   +1 more source

Chromosome-level draft genome assembly of Hypomesus nipponensis reveals transposable element expansion reshaping the genome structure

Frontiers in Genetics
Hypomesus nipponensis a commercially valuable fish within the Osmeriformes order, is naturally found in northeastern Asia and has been extensively introduced for commercial purposes across eastern Asia.
Chenzhao Zhu, Chenzhao Zhu, Youyi Kuang, Zhe Li, Fujiang Tang, Fujiang Tang   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The Human Genome Prodject

, 1999
sic; Project.
Zimmern, Ron
core  

A comprehensive analysis of the genomic and proteomic profiles of a megalocytivirus isolated from Larimichthys crocea

Frontiers in Microbiology
IntroductionThe prevalence of viral diseases has posed significant challenges to the sustainable development of large yellow croaker (Larimichthys crocea) aquaculture, with megalocytivirus being one of the primary viral pathogens affecting this species ...
Xiaodong Liu, Xiaodong Liu, Hongshu Chi, Hongshu Chi, Xixi Yang, Xixi Yang, Zaiyu Zheng, Zaiyu Zheng, Chunhua Zhu, Yunkun Wu, Yunkun Wu, Wei-Jen Chang, Hui Gong, Hui Gong, Hui Gong   +14 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Chromosome-Level Genome Assembly of Apoderus dimidiatus Voss (Coleoptera: Attelabidae): Insights into Evolution and Behavior

Insects
Attelabidae insects have attracted much attention due to their unique leaf rolling behavior before oviposition. However, the lack of genomic data makes it difficult to understand the molecular mechanism behind their behavior and their evolutionary ...
Meng Xie, Yuhao Yao, Yuling Feng, Lei Xie, Chuyang Mao, Jinwu He, Xueyan Li, Qingyong Ni   +7 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source