Results 161 to 170 of about 1,891,272 (273)

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Expression of animal virus genomes [PDF]

, 1971
David Baltimore
openalex   +2 more sources

Corrigendum: Genome and Environmental Activity of a Chrysochromulina parva Virus and Its Virophages

Frontiers in Microbiology, 2019
Joshua M. A. Stough, Natalya Yutin, Yuri V. Chaban, Mohammed Moniruzzaman, Eric R. Gann, Helena L. Pound, Morgan M. Steffen, Jenna N. Black, Eugene V. Koonin, Steven W. Wilhelm, Steven M. Short   +10 more
doaj   +1 more source

STUDIES ON MENTHA AQUATICA L. AND ITS GENOME ANALYSIS. II. : Genome Analysis in the Genus Mentha, Part 7

, 1969
Nagamori Ikeda, Seiroku Ono
openalex   +2 more sources

Development of a cost-effective high-throughput mid-density 5K genotyping assay for germplasm characterization and breeding in groundnut. [PDF]

Plant Genome
Pandey MK, Sharma V, Khan AW, Joshi P, Gangurde SS, Bajaj P, Janila P, Chitikineni A, Bhat R, Motagi BN, Sangh C, Radhakrishnan T, Bera SK, Gorjanc G, Gujjula KR, Hall N, Carrasco CD, Arjun K, Chandram S, Varshney RK.   +19 more
europepmc   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Studies on Mentha spicata. L. var crispa BENTH. (Genome analysis in Mentha. Part 1)

, 1960
Nagamori Ikeda, Seiroku Udo, Masaru Nakamura   +2 more
openalex   +2 more sources

Properties of the genome in normal and SV-40 transformed WI-38 human diploid fibroblasts. III. Turnover of nonhistone chromosomal proteins and their phosphate groups [PDF]

, 1975
Margarida O. Krause, Lewis J. Kleinsmith, Gary S. Stein   +2 more
openalex   +1 more source

Landscape of rare-allele variants in cultivated and wild soybean genomes. [PDF]

Plant Genome
Liu Z, Shi X, Yang Q, Li Y, Yang C, Zhang M, An YC, Nguyen HT, Yan L, Song Q.   +9 more
europepmc   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source