Results 221 to 230 of about 4,660,063 (378)

Genomics

Vojnosanitetski pregled, 2006
openaire   +4 more sources

Genomes within genomes [PDF]

Nature, 2007
openaire   +1 more source

FLASH: fast length adjustment of short reads to improve genome assemblies

Bioinform., 2011
Tanja Magoc, Steven Salzberg
semanticscholar   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Diverse reference genomes detect variants in the US winter wheat. [PDF]

Plant Genome
Parker K, Wang Z, Rauf Y, Gao L, Poland J, Rudd J, Ibrahim A, Liu S.   +7 more
europepmc   +1 more source

Multiplex Genome Engineering Using CRISPR/Cas Systems

Science, 2013
Le Cong, F. Ran, David B. T. Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, P. Hsu, Xuebing Wu, Wenyan Jiang, L. Marraffini, Feng Zhang   +10 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Progress in Flax Genome Assembly from Nanopore Sequencing Data. [PDF]

Plants (Basel)
Pushkova EN, Arkhipov AA, Bolsheva NL, Rozhmina TA, Zhuchenko AA, Borkhert EV, Barsukov NM, Oleshnya GA, Milovanova AV, Moskalenko OD, Kostromskoy FD, Ivankina EA, Dvorianinova EM, Krupskaya DA, Melnikova NV, Dmitriev AA.   +15 more
europepmc   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Chromosome-level genome assembly of the predatory stink bug, Eocanthecona furcellata (Wolff). [PDF]

Sci Data
Hu QL, Zhuo JC, Zhang CX.
europepmc   +1 more source