Results 31 to 40 of about 3,409,680 (280)

Are we there yet? : reliably estimating the completeness of plant genome sequences [PDF]

open access: yes, 2016
Genome sequencing is becoming cheaper and faster thanks to the introduction of next-generation sequencing techniques. Dozens of new plant genome sequences have been released in recent years, ranging from small to gigantic repeat-rich or polyploid genomes.
Ruttink, Tom   +2 more
core   +3 more sources

Reference Based Genome Compression [PDF]

open access: yes, 2012
DNA sequencing technology has advanced to a point where storage is becoming the central bottleneck in the acquisition and mining of more data. Large amounts of data are vital for genomics research, and generic compression tools, while viable, cannot ...
Chern, Bobbie   +5 more
core   +2 more sources

Tetraodon genome confirms Takifugu findings : most fish are ancient polyploids [PDF]

open access: yes, 2004
An evolutionary hypothesis suggested by studies of the genome of the tiger pufferfish Takifugu rubripes has now been confirmed by comparison with the genome of a close relative, the spotted green pufferfish Tetraodon nigroviridis.
Van de Peer, Yves
core   +1 more source

100K Pathogen Genome Project. [PDF]

open access: yes, 2017
The 100K Pathogen Genome Project is producing draft and closed genome sequences from diverse pathogens. This project expanded globally to include a snapshot of global bacterial genome diversity.
Weimer, Bart C
core   +1 more source

GIVE: portable genome browsers for personal websites. [PDF]

open access: yes, 2018
Growing popularity and diversity of genomic data demand portable and versatile genome browsers. Here, we present an open source programming library called GIVE that facilitates the creation of personalized genome browsers without requiring a system ...
Alvin Zheng   +31 more
core   +2 more sources

Transcription as a Threat to Genome Integrity [PDF]

open access: yes, 2016
Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and genome rearrangements, that constitute the basis for evolution.
Aguilera López, Andrés   +1 more
core   +1 more source

CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods

open access: yesGenome Biology
Background The Critical Assessment of Genome Interpretation (CAGI) aims to advance the state-of-the-art for computational prediction of genetic variant impact, particularly where relevant to disease.
The Critical Assessment of Genome Interpretation Consortium
doaj   +1 more source

Comprehensive genomic characterization defines human glioblastoma genes and core pathways. [PDF]

open access: yes, 2008
Human cancer cells typically harbour multiple chromosomal aberrations, nucleotide substitutions and epigenetic modifications that drive malignant transformation.
Cancer Genome Atlas Research Network
core   +1 more source

Reduced mutation rate and increased transformability of transposon-free Acinetobacter baylyi ADP1-ISx [PDF]

open access: yes, 2017
The genomes of most bacteria contain mobile DNA elements that can contribute to undesirable genetic instability in engineered cells. In particular, transposable insertion sequence (IS) elements can rapidly inactivate genes that are important for a ...
Barrick, Jeffrey E   +3 more
core   +2 more sources

Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez   +14 more
wiley   +1 more source

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