Results 31 to 40 of about 4,524,973 (357)

Monitoring the spread of the SARS-CoV-2 (Coronaviridae: Coronavirinae: Betacoronavirus; Sarbecovirus) variants in the Moscow region using targeted high-throughput sequencing

Вопросы вирусологии, 2021
Introduction. Since the outbreak of the COVID-19 pandemic caused by SARS-CoV-2 novel coronavirus, the international community has been concerned about the emergence of mutations altering some biological properties of the pathogen like increasing its ...
N. I. Borisova, I. A. Kotov, A. A. Kolesnikov, V. V. Kaptelova, A. S. Speranskaya, L. Yu. Kondrasheva, E. V. Tivanova, K. F. Khafizov, V. G. Akimkin   +8 more
doaj   +1 more source

Reference genome and comparative genome analysis for the WHO reference strain for Mycobacterium bovis BCG Danish, the present tuberculosis vaccine [PDF]

, 2019
Background: Mycobacterium bovis bacillus Calmette-Guerin (M. bovis BCG) is the only vaccine available against tuberculosis (TB). In an effort to standardize the vaccine production, three substrains, i.e. BCG Danish 1331, Tokyo 172-1 and Russia BCG-1 were
Borgers, Katlyn, Callewaert, Nico, Festjens, Nele, Lin, Yao-Cheng, Michielsen, Gitte, Ou, Jheng-Yang, Plets, Evelyn, Tiels, Petra, Van Hecke, Annelies, Zheng, Po-Xing   +9 more
core   +2 more sources

SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing

J. Comput. Biol., 2012
The lion's share of bacteria in various environments cannot be cloned in the laboratory and thus cannot be sequenced using existing technologies. A major goal of single-cell genomics is to complement gene-centric metagenomic data with whole-genome ...
A. Bankevich, S. Nurk, D. Antipov, A. Gurevich, M. Dvorkin, Alexander S. Kulikov, Valery M. Lesin, S. Nikolenko, Son K. Pham, Andrey D. Prjibelski, A. Pyshkin, Alexander Sirotkin, Nikolay Vyahhi, G. Tesler, M. Alekseyev, P. Pevzner   +15 more
semanticscholar   +1 more source

Lassa fever in Benin: description of the 2014 and 2016 epidemics and genetic characterization of a new Lassa virus

Emerging Microbes and Infections, 2020
We report two outbreaks of Lassa fever that occurred in Benin in 2014 and 2016 with 20 confirmed cases and 50% (10/20) mortality. Benin was not previously considered to be an endemic country for Lassa fever, resulting in a delay to diagnose the disease ...
Anges Yadouleton, Caroline Picard, Toni Rieger, Frederic Loko, Daniel Cadar, Emile Cossi Kouthon, Emmanuel Obolli Job, Honoré Bankolé, Lisa Oestereich, Fernand Gbaguidi, Meike Pahlman, Beate Becker-Ziaja, Alexandra Journeaux, Delphine Pannetier, Stéphane Mély, Stéphanie Mundweiler, Damien Thomas, Leon Kohossi, Raoul Saizonou, Clement Glele Kakaï, Magloire Da Silva, Sonia Kossoubedie, André Lukusa Kakonku, Pierre M’Pelé, Stephan Gunther, Sylvain Baize, Elisabeth Fichet-Calvet   +26 more
doaj   +1 more source

Genome of Drosophila suzukii, the spotted wing drosophila. [PDF]

, 2013
Drosophila suzukii Matsumura (spotted wing drosophila) has recently become a serious pest of a wide variety of fruit crops in the United States as well as in Europe, leading to substantial yearly crop losses.
Begun, David J, Chiu, Joanna C, Cridland, Julie M, Hamby, Kelly A, Hamm, Christopher A, Jiang, Xuanting, Kwok, Rosanna S, Lee, Ernest K, Saelao, Perot, Walton, Vaughn M, Zalom, Frank G, Zhang, Guojie, Zhao, Li   +12 more
core   +2 more sources

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Genome Biology, 2009
Bowtie is an ultrafast, memory-efficient alignment program for aligning short DNA sequence reads to large genomes. For the human genome, Burrows-Wheeler indexing allows Bowtie to align more than 25 million reads per CPU hour with a memory footprint of ...
Ben Langmead, C. Trapnell, Mihai Pop, S. Salzberg   +3 more
semanticscholar   +1 more source

Live pigs produced from genome edited zygotes [PDF]

, 2013
Transcription activator-like effector nuclease (TALEN) and zinc finger nuclease (ZFN) genome editing technology enables site directed engineering of the genome.
AJ Clark, AM Guerts, CJ Palgrave, D Yang, DF Carlson, FD Urnov, ID Carbery, J Hauschild, JC Miller, JJ Whyte, SC Fahrenkrug, T Flisokowska, VM Bedell, WS Tan   +13 more
core   +1 more source

The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data.

Genome Research, 2010
Next-generation DNA sequencing (NGS) projects, such as the 1000 Genomes Project, are already revolutionizing our understanding of genetic variation among individuals.
A. McKenna, M. Hanna, E. Banks, A. Sivachenko, K. Cibulskis, A. Kernytsky, K. Garimella, D. Altshuler, S. Gabriel, M. Daly, M. DePristo   +10 more
semanticscholar   +1 more source

Life in High Salt Concentrations with Changing Environmental Conditions: Insights from Genomic and Phenotypic Analysis of Salinivibrio sp.

Microorganisms, 2019
Life in salt pans with varying chemical compositions require special adaptation strategies at both the physiological and molecular level. The Marakkanam salt pan in South India is characterized with a high fluctuation in salinity (19−490 ppt ...
Jojy John, Vinu Siva, Kumari Richa, Aditya Arya, Amit Kumar   +4 more
doaj   +1 more source

Chromosomal mapping of rDNAs and H3 histone sequences in the grasshopper rhammatocerus brasiliensis (acrididae, gomphocerinae): extensive chromosomal dispersion and co-localization of 5S rDNA/H3 histone clusters in the A complement and B chromosome

Molecular Cytogenetics, 2011
Background Supernumerary B chromosomes occur in addition to standard karyotype and have been described in about 15% of eukaryotes, being the repetitive DNAs the major component of these chromosomes, including in some cases the presence of multigene ...
Oliveira Nathalia L, Cabral-de-Mello Diogo C, Rocha Marília F, Loreto Vilma, Martins Cesar, Moura Rita C   +5 more
doaj   +1 more source