Results 51 to 60 of about 3,743,554 (329)

Butterfly genome reveals promiscuous exchange of mimicry adaptations among species. [PDF]

, 2016
Author's manuscript, Europe PMC version. Published in final edited form as: Nature. 2012 July 5; 487(7405): 94–98. doi:10.1038/nature11041.The evolutionary importance of hybridization and introgression has long been debated.
Heliconius Genome Consortium
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Validation of a guidelines-based digital tool to assess the need for germline cancer genetic testing

Hereditary Cancer in Clinical Practice
Background Efficient and scalable solutions are needed to identify patients who qualify for germline cancer genetic testing. We evaluated the clinical validity of a brief, patient-administered hereditary cancer risk assessment digital tool programmed to ...
Callan D. Russell, Ashley V. Daley, Durand R. Van Arnem, Andi V. Hila, Kiley J. Johnson, Jill N. Davies, Hanah S. Cytron, Kaylene J. Ready, Cary M. Armstrong, Mark E. Sylvester, Colleen A. Caleshu   +10 more
doaj   +1 more source

Whole-Genome Sequence of Colletotrichum brevisporum Causing Anthracnose on Papaya (Carica papaya)

PhytoFrontiers
Colletotrichum spp. are the causal agents of papaya anthracnose, which seriously affects the quality and economic value of papaya fruits. Among them, Colletotrichum brevisporum is a new and important causal pathogen of anthracnose in papaya.
Min Yang, Chenping Zhou, Ruibin Kuang, Xiaming Wu, Yuerong Wei   +4 more
doaj   +1 more source

HUMAN PARVOVIRUS В19: VIRUS CHARACTERISTICS, DISTRIBUTION AND DIAGNOSTICS OF PARVOVIRUS INFECTION

Инфекция и иммунитет, 2014
. The modern data about morphology as well as structural and functional organization of the parvovirus B19 genome, circulating virus genotypes are presented in the review.
I. N. Lavrentyeva, A. Y. Antipova
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Expression of concern for global biomedical research by the human genome organization (HUGO)

Human Genomics
Cuts to US science funding will stall advances in genomics affecting public health, rare disease and cancer diagnostics and therapeutics in the US and around the world.
Ada Hamosh, Fabiana Arzuaga, Karen B. Avraham, Zilfalil Bin Alwi, Anne Bowcock, Sir John Burn, Piero Carninci, Collet Dandara, Iscia Lopes-Cendes, Leon Mutesa, Partha P. Majumder, Juergen K.V. Reichardt, Joris A. Veltman   +12 more
doaj   +1 more source

MOLECULAR-GENETIC BASIS OF PHYSIOLOGY AND PATHOGENICITY OF COXIELLA BURNETII

Инфекция и иммунитет, 2014
. The agent of Q-fever Coxiella burnetii is unusual intracellular pathogen which is possessed of biggest transporting and metabolic abilities in compare with microorganisms with similar parasitic strategy.
Yu. A. Panpherova
doaj   +1 more source

Transcription as a Threat to Genome Integrity [PDF]

, 2016
Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and genome rearrangements, that constitute the basis for evolution.
Aguilera López, Andrés, Gaillard, Hélène   +1 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source