Molecular Cytogenetics, 2011 Background Supernumerary B chromosomes occur in addition to standard karyotype and have been described in about 15% of eukaryotes, being the repetitive DNAs the major component of these chromosomes, including in some cases the presence of multigene ...
Oliveira Nathalia L +5 more
doaj +1 more source
iCN718, an Updated and Improved Genome-Scale Metabolic Network Reconstruction of Acinetobacter baumannii AYE. [PDF]
, 2018 Acinetobacter baumannii has become an urgent clinical threat due to the recent emergence of multi-drug resistant strains. There is thus a significant need to discover new therapeutic targets in this organism.
Kavvas, Erol +4 more
core +2 more sources
Trinity: reconstructing a full-length transcriptome without a genome from RNA-Seq data
Nature Biotechnology, 2011 Massively parallel sequencing of cDNA has enabled deep and efficient probing of transcriptomes. Current approaches for transcript reconstruction from such data often rely on aligning reads to a reference genome, and are thus unsuitable for samples with a
M. Grabherr +20 more
semanticscholar +1 more source
Genome BiologyBackground The Critical Assessment of Genome Interpretation (CAGI) aims to advance the state-of-the-art for computational prediction of genetic variant impact, particularly where relevant to disease.
The Critical Assessment of Genome Interpretation Consortium
doaj +1 more source
A Genome Sequence Resource of Diaporthe nobilis Causing Kiwifruit Rot
PhytoFrontiersDiaporthe spp. are a significant plant pathogen causing wood canker, blight, dieback, and fruit decay in numerous economically important plant hosts worldwide. D.
Huanhuan Li +4 more
doaj +1 more source
Comprehensive genomic characterization defines human glioblastoma genes and core pathways. [PDF]
, 2008 Human cancer cells typically harbour multiple chromosomal aberrations, nucleotide substitutions and epigenetic modifications that drive malignant transformation.
Cancer Genome Atlas Research Network
core +1 more source
The Janthinobacterium sp. HH01 genome encodes a homologue of the V. cholerae CqsA and L. pneumophila LqsA autoinducer synthases [PDF]
, 2013 Janthinobacteria commonly form biofilms on eukaryotic hosts and are known to synthesize antibacterial and antifungal compounds. Janthinobacterium sp. HH01 was recently isolated from an aquatic environment and its genome sequence was established.
Blokesch, Melanie +20 more
core +4 more sources
Merqury: reference-free quality, completeness, and phasing assessment for genome assemblies
Genome Biology, 2020 Recent long-read assemblies often exceed the quality and completeness of available reference genomes, making validation challenging. Here we present Merqury, a novel tool for reference-free assembly evaluation based on efficient k-mer set operations.
A. Rhie +3 more
semanticscholar +1 more source
Evaluating the Genetic Overlap Between Congenital Heart Disease and Neuroblastoma Risk
Pediatric Blood &Cancer, EarlyView.ABSTRACT Children with congenital heart disease (CHD) have elevated neuroblastoma (NB) risk, potentially due to shared neural crest origins. We analyzed rare exonic de novo single‐nucleotide variants in 702 CHD and 454 NB trios from the Neuroblastoma Epidemiology in North America Study, Gabriella Miller Kids First Program, and a published cohort. Seven
Ji Yun Tark +7 more
wiley +1 more source
Whole-Genome Sequence of Colletotrichum brevisporum Causing Anthracnose on Papaya (Carica papaya)
PhytoFrontiersColletotrichum spp. are the causal agents of papaya anthracnose, which seriously affects the quality and economic value of papaya fruits. Among them, Colletotrichum brevisporum is a new and important causal pathogen of anthracnose in papaya.
Min Yang +4 more
doaj +1 more source