Results 131 to 140 of about 1,597,445 (261)

Genome Analysis [PDF]

International Journal of Infectious Diseases, 2008
openaire   +2 more sources

QStrain: an interactive platform for viral genome analysis and nucleic acid therapeutic design. [PDF]

BMC Bioinformatics
Jeong E, Lee S, Jeong S, Lee H, Kim KC, Lee JY, Shin M, Yoon S.   +7 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Phylogenetic Relationships of Five Phallales Species Based on Mitochondrial Genome Analysis. [PDF]

J Fungi (Basel)
Wang Y, Li D, Wang G, Guo Z, Wang X, Liu H.   +5 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Whole-genome analysis of a novel <i>Pandoraea sputorum</i> lineage causing high-mortality bloodstream infections. [PDF]

Microb Genom
Wu H, Liu L, Li S, Zhang P, Xing Z, Huang Q, Kuang D, Liu W, Chen C, Xia Q.   +9 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Comparative genome analysis provides a foundation for defining salvinorin A biosynthesis in Salvia divinorum. [PDF]

Nat Commun
Li H, Sun Y, Xu W, Sun B, Wu S, Li C, Zhao J, Martin C, Tatsis EC.   +8 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

The complete mitochondrial genome analysis of <i>Elachiptera decipiens</i> (Loew, 1863) (Diptera: Chloropidae). [PDF]

Mitochondrial DNA B Resour
Gu YY, Guo Y, Zhang WL, Zhang HJ, Dai AM, Zhang H.   +5 more
europepmc   +1 more source