Results 171 to 180 of about 27,766,143 (267)

Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome".

Proceedings of the National Academy of Sciences of the United States of America, 2005
H. Tettelin, V. Masignani, M. Cieslewicz, C. Donati, D. Medini, N. Ward, Samuel V. Angiuoli, J. Crabtree, Amanda L. Jones, A. S. Durkin, R. Deboy, Tanja Davidsen, Marirosa Mora, M. Scarselli, Immaculada Margarit y Ros, J. Peterson, Christopher Hauser, Jaideep P. Sundaram, W. Nelson, R. Madupu, L. Brinkac, R. Dodson, M. J. Rosovitz, S. Sullivan, Sean C. Daugherty, D. Haft, J. Selengut, M. Gwinn, Liwei Zhou, Nikhat Zafar, H. Khouri, D. Radune, George I Dimitrov, Kisha L. Watkins, K. O'Connor, Shannon Smith, T. Utterback, O. White, C. Rubens, G. Grandi, L. Madoff, D. Kasper, J. Telford, M. Wessels, R. Rappuoli, C. Fraser   +45 more
semanticscholar   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Genome analysis of a cluster EF bacteriophage LordBart isolated from soil in Tennessee. [PDF]

MicroPubl Biol
Markov S, Fecteau C, Jones T, Lee M, Thornton M.   +4 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Nallo: a Nextflow pipeline for comprehensive human long-read genome analysis. [PDF]

Bioinformatics
Lenner F, Jemt A, Peña Pérez L, Neethiraj R, Pruisscher P, Schmitz D, Renevey A, Corcoran P, Nilsson D, Eisfeldt J, Lindstrand A, Wirta V, Ameur A, Feuk L.   +13 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Pan-genome analysis of soybean terpene synthase identifies <i>GmTPS20</i> as a defense-related linalool synthase. [PDF]

Front Plant Sci
Han T, Liu H, Lu T, Jiang C, Wang C, Miao G.   +5 more
europepmc   +1 more source

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

Science, 2009
Nicholas T. Ingolia, Sina Ghaemmaghami, J. R. Newman, J. Weissman   +3 more
semanticscholar   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Fifteen Years of the Genome Analysis Toolkit as the De Facto Standard in Short-Read Variant Calling. [PDF]

Int J Mol Sci
Blazyte A, Le L, Lee J, Bayarsaikhan D, Lee B.   +4 more
europepmc   +1 more source