Results 111 to 120 of about 1,479,681 (326)
BMC Genomics, 2013 Background The green anole lizard, Anolis carolinensis, is a key species for both laboratory and field-based studies of evolutionary genetics, development, neurobiology, physiology, behavior, and ecology. As the first non-avian reptilian genome sequenced,
Eckalbar Walter L +9 more
doaj +1 more source
ProTISA: a comprehensive resource for translation initiation site annotation in prokaryotic genomes [PDF]
, 2007 Gangqing Hu +5 more
openalex +1 more source
Comparative Annotation Toolkit (CAT)—simultaneous clade and personal genome annotation
bioRxiv, 2017 The recent introductions of low-cost, long-read, and read-cloud sequencing technologies coupled with intense efforts to develop efficient algorithms have made affordable, high-quality de novo sequence assembly a realistic proposition.
Ian T. Fiddes +12 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Vgas: A Viral Genome Annotation System
Frontiers in Microbiology, 2019 The in-depth study of viral genomes is of great help in many aspects, especially in the treatment of human diseases caused by viral infections. With the rapid accumulation of viral sequencing data, improved, or alternative gene-finding systems have ...
Kai-Yue Zhang +5 more
doaj +1 more source
Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and Other Coronaviruses: A Genome-wide Comparative Annotation and Analysis [PDF]
, 2021 Mohammed Tarique +10 more
openalex +1 more source
KEGG as a reference resource for gene and protein annotation
Nucleic Acids Res., 2015 KEGG (http://www.kegg.jp/ or http://www.genome.jp/kegg/) is an integrated database resource for biological interpretation of genome sequences and other high-throughput data.
M. Kanehisa +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Ten steps to get started in Genome Assembly and Annotation [version 1; referees: 2 approved]
F1000Research, 2018 As a part of the ELIXIR-EXCELERATE efforts in capacity building, we present here 10 steps to facilitate researchers getting started in genome assembly and genome annotation.
Victoria Dominguez Del Angel +15 more
doaj +1 more source
Annotated Bioinformatic Pipelines for Genome Assembly and Annotation of Mitochondrial Genomes
BIO-PROTOCOLMitochondrial genomes (mitogenomes) display relatively rapid mutation rates, low sequence recombination, high copy numbers, and maternal inheritance patterns, rendering them valuable blueprints for mapping lineages, uncovering historical migration patterns, understanding intraspecific population dynamics, and investigating how environmental pressures ...
Jessica Winn +2 more
openaire +3 more sources