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Comparative Genome Annotation Systems
2006Understanding the genetic content of a genome is a very important but challenging task. One of the most effective methods to annotate a genome is to compare it to the genomes that are already sequenced and annotated. This chapter is to survey systems that can be used for annotating genomes by comparing multiple genomes and discusses important issues in
Kwangmin Choi, Sun Kim
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Newly sequenced genomes are being added to the tree of life at an unprecedented fast pace. A large proportion of such new genomes are phylogenetically close to previously sequenced and annotated genomes. In other cases, whole clades of closely related species or strains ought to be annotated simultaneously.
Stefanie, Nachtweide+2 more
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Stefanie, Nachtweide+2 more
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Annotating the genome of Medicago truncatula
Current Opinion in Plant Biology, 2006Medicago truncatula will be among the first plant species to benefit from the completion of a whole-genome sequencing project. For each of these species, Arabidopsis, rice and now poplar and Medicago, annotation, the process of identifying gene structures and defining their functions, is essential for the research community to benefit from the sequence
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Genome Annotation and Analysis
2003In the preceding chapter, we gave a brief overview of the methods that are commonly used for identification of protein-coding genes and analysis of protein sequences. Here, we turn to one of the main subjects of this book, namely how these methods are applied to the task of primary analysis of genomes, which often goes under the name of “genome ...
Eugene V. Koonin, Michael Y. Galperin
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2008
Since the mid-eighties, laboratories world-wide have endeavoured to determine the complete sequence of genomes from all kinds of living organisms. The first complete sequence of DNA bacteriophage ΦX174 appeared in 1978 (5386 nt (Sanger et al. 1978)), followed by that of bacteriophage lambda, using a shotgun technology, published in 1982 (48,502 bp ...
Claudine Médigue+2 more
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Since the mid-eighties, laboratories world-wide have endeavoured to determine the complete sequence of genomes from all kinds of living organisms. The first complete sequence of DNA bacteriophage ΦX174 appeared in 1978 (5386 nt (Sanger et al. 1978)), followed by that of bacteriophage lambda, using a shotgun technology, published in 1982 (48,502 bp ...
Claudine Médigue+2 more
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The Grapevine Genome Annotation
2019The release of the grapevine genome sequence has allowed the generation of invaluable data on gene function, providing tools for a better understanding of the plant biology. To capitalize on this information, the annotation of the genome has been an ongoing effort performed by the research community on that species.
Grant R. Cramer, Jérôme Grimplet
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2019
Gene annotation is considered an important step in understanding the functioning of the genome. With a good genome assembly in place, gene prediction and annotation is done to understand the functional aspects of the genome. However, the process becomes more complex due to the presence of alternative splicing and other regulatory factors that affect ...
Malali Gowda, Nagesh A. Kuravadi
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Gene annotation is considered an important step in understanding the functioning of the genome. With a good genome assembly in place, gene prediction and annotation is done to understand the functional aspects of the genome. However, the process becomes more complex due to the presence of alternative splicing and other regulatory factors that affect ...
Malali Gowda, Nagesh A. Kuravadi
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Annotation of the Human Genome
Science, 2000The News article “Are sequencers ready to ‘annotate’ the human genome?” by Elizabeth Pennisi (special issue on the Drosophila Genome, 24 Mar., p. [2183][1]) is especially timely and provocative. Pennisi mentions two ideas: a small group gathering at a centralized annotation jamboree, or a distributed, Web-based system that would allow anyone to ...
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Introduction to Genome Annotation
2020This exercise is an adaptation of the Annotation Lesson by Rosenwald et al. It introduces the use of bioinformatics tools to extract information from genome databases. It is a basic lesson on genome annotation databases.
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Annotation of the Tomato Genome
2016The annotation of the tomato genome performed by the iTAG consortium (international Tomato Annotation Group) relied on a pipeline operating as a distributed, worldwide network of resources and experts. It used SGN (http://solgenomics.net/) as a central data repository and exchange node.
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