Results 211 to 220 of about 452,095 (265)

A chromosomal haplotype-resolved genome assembly of Cuphea hookeriana. [PDF]

Sci Data
Gu C, Wang J, Zhang G, Peng D, Li Z, Ren S, Wu Z, Yang L.   +7 more
europepmc   +1 more source

CREAT: A CRISPR‐Based Genome Trimming Strategy for Systematic Identification of Dispensable Regions and Rapid Genome Reduction

Advanced Science, EarlyView.
Current genome‐reduction methods work in a trial‐and‐error fashion, constituting a long‐standing bottleneck in the research. We developed CREAT (CRISPR‐based genome trimming with a multi‐homology‐arm template), a CRISPR‐based genetic approach that enables systematically classifying essential versus non‐essential genomic regions and subsequently ...
Guanhua Yuan, Zhe Gao, Yingxuan Qi, Yang Zhang, Xuhui Tian, Pengpeng Zhao, Xu Feng, Qunxin She   +7 more
wiley   +1 more source

Chromosome-level genome assembly and annotation of the moon jellyfish Aurelia coerulea. [PDF]

Sci Data
Hu X, Guo Y, Zhang Z, Wang L, Chen D, Zhuang Z, Wang M, Liu S, Feng S.   +8 more
europepmc   +1 more source

Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing

Advanced Science, EarlyView.
A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo, Yuyao Qu, Zhengyan Ye, Zheng Li, Yuanyan Zhang, Longjiong Luo, Shaokang Li, Wei Zhao, Ming Wang, Ralph Bock, Jianmin Wan, Junjie Tan   +11 more
wiley   +1 more source

Chromosome-scale reference genome assembly and annotation of Prunus scopulorum. [PDF]

Sci Data
Guo T, Li X, Zhu D, Shen B, Hong P, Zhang L, Sun S, Wang J, Qiao Q, Liu Q.   +9 more
europepmc   +1 more source

Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction

Advanced Science, EarlyView.
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng, Jing Sheng, Ben Niu, Wenjuan Fu, Yingjie Yang, Zuowei Xie, Shuang Xie, Yunxuan He, Meilin Gong, Jue Wang, Yan Pi, Ming Chen, Kai Chang   +12 more
wiley   +1 more source

The chromosomal-level genome assembly and annotation of Phyllospadix iwatensis (Surfgrass). [PDF]

Sci Data
Wang J, Wang D, Zhao K, Liu Z, Zhang Q.
europepmc   +1 more source

Chromosome-Level Genome Assembly and Annotation of Piptanthus nepalensis (Hook.) Sweet. [PDF]

Sci Data
Zhang J, Zeng Z, Bonjor N, Norbu N, Tso N, Tan X, Wang Y, Wang J, Qiong.   +8 more
europepmc   +1 more source

Chromosome-scale genome assembly and characterization of Saccharomycopsis schoenii, a necrotrophic predatory yeast. [PDF]

G3 (Bethesda)
Kriti D, Barazandeh M, Ogbede JU, Giaever G, Nislow C.   +4 more
europepmc   +1 more source