Results 231 to 240 of about 452,095 (265)
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2018
Genome assembly uses sequence similarity to go from sequencing reads to longer contiguous sequences (contigs). Scaffolds are contigs linked together by gaps where the order and orientation of the contigs is known but the exact sequence connecting two contigs is unknown, represented by Ns which estimate the gap length.
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Genome assembly uses sequence similarity to go from sequencing reads to longer contiguous sequences (contigs). Scaffolds are contigs linked together by gaps where the order and orientation of the contigs is known but the exact sequence connecting two contigs is unknown, represented by Ns which estimate the gap length.
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Generating a Genome Assembly with PCAP
Current Protocols in Bioinformatics, 2005AbstractThis unit describes how to use the Parallel Contig Assembly Program (PCAP) to assemble the data produced by a whole‐genome shotgun sequencing project. We present a basic protocol for using PCAP on a multiprocessor computer in a 300‐Mb genome assembly project. A support protocol to prepare input files for PCAP is also described.
Xiaoqiu, Huang, Shiaw-Pyng, Yang
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Assembly of the Reovirus Genome
1998During the early days of molecular virology, the presumed monomolecular nature of their genomes was considered to be one of the primary virtues of viruses. However, in 1969, irrefutable evidence surfaced that reovirus genomes consist not of one, but of ten molecules of double-stranded (ds)RNA (Shatkin et al. 1968).
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Genome Assembly on a Multicore System
2013 12th IEEE International Conference on Trust, Security and Privacy in Computing and Communications, 2013The genome assembly problem is to generate the original DNA sequence of an organism from a large set of short (400bp-500bp) overlapping fragments. The assembly problem is challenging particularly in presence of repeats, which are multiple identical or nearly identical stretches of DNA. MIRA is an open source assembler, which is widely used by biologist
Abhishek Biswas +2 more
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Particle Assembly and Genome Packaging
2003Foamy virus (FV) replication is distinct from that of all other retroviruses in many respects, including viral assembly. In fact, the viral assembly pathway is rather similar to that of hepadnaviruses such as hepatitis B virus. Foamy virus Gag does not contain landmark retroviral assembly domains such as the major homology region, Cys-His boxes, or a ...
M L, Linial, S W, Eastman
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Genome Assembly, Rearrangement, and Repeats
Chemical Reviews, 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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Perfecting bacterial genome assembly
2022DNA sequencers cannot directly provide an organism's complete genome sequence. Rather, they produce fragmented and error-containing pieces of the genome (reads), and the computational task of reconstructing a genome from sequencing reads is known as assembly.
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The Assembly of the Human and Mouse Genomes
2002Paired-read shotgun sequencing of a genome consists of randomly sampling segments of a fixed length, say 10,000 base pairs (10Kbp), and directly determining a “read” of 500 to 700bp at the two ends of each segment with an automated DNA sequencing instrument.
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Genome Assembler for Repetitive Sequences
2012The article presents a new algorithm for random DNA fragment assembly. The algorithm uses an extended de Bruijn graph that stores information of reads coverage. It is able to reconstruct consecutive repetitive sequences longer than reads and to process large amount of data provided by new generation sequencers.
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Fusarium Genome Sequencing and Assembly
Fusarium is a genus of significant concern and interest. With the development of omics technologies, sequencing and assembling fungal genomes became widely available. To date, numerous Fusarium genomes were deposited in genomic databases. This chapter highlights the importance of studying Fusarium species and discusses the structure and peculiarities ...Ekaterina M, Dvorianinova +2 more
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