Results 241 to 250 of about 757,981 (296)

Chromosome-Level Genome Assembly of Donacia provosti. [PDF]

Sci Data
Liu H, Ma L, Sun Y, Ahsan MH, Wu C, Gong C, Li L, Luo C.   +7 more
europepmc   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

Chromosome-level genome assembly of the medicinal plant Ophiorrhiza japonica Blume. [PDF]

Sci Data
Tang X, Liu Y, Liao Y, Tang M, Yang T, Yi Y.   +5 more
europepmc   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Correction to: A haplotype-resolved genome assembly of the bocaccio rockfish. [PDF]

J Hered
europepmc   +1 more source

Minimum virtual dataset for reproducible triploid de novo genome assembly. [PDF]

Sci Data
Ootsuki R.
europepmc   +1 more source

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR‐NK Therapeutic Strategies

Advanced Science, EarlyView.
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim, Seona Jo, In‐Hwan Jang, Yu‐Jin Kim, Youngmee Jung, Junhyoung Ahn, Hyungjun Lim, Jae Jong Lee, Kangwon Lee, Tae‐Don Kim, Su A Park   +10 more
wiley   +1 more source

First high-quality genome assembly of Umbelopsis nana isolated from forest soil. [PDF]

G3 (Bethesda)
Iizuka R, Suzuki T, Watanabe N, Tabima JF, Hibbett D, Katayama Y, Yoshida M.   +6 more
europepmc   +1 more source

ZSL Orchestrates Synaptonemal Complex Assembly as a Central Region Scaffold to Ensure Synapsis Fidelity and Crossover Control in Polyploid Meiosis

Advanced Science, EarlyView.
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng, Shaochen Jia, Fei Cao, Cuiping Liu, Heshuang Zhang, Gang Xu, Jixin Zhuang, Yashi Zhang, Can Liu, Yuhang Zhao, Zilin Guo, Xinjie Yuan, Jiaqing Yang, Lei Chu, Bowei Cai, Hu Zhao, Chao Yang   +16 more
wiley   +1 more source

Progress in Flax Genome Assembly from Nanopore Sequencing Data. [PDF]

Plants (Basel)
Pushkova EN, Arkhipov AA, Bolsheva NL, Rozhmina TA, Zhuchenko AA, Borkhert EV, Barsukov NM, Oleshnya GA, Milovanova AV, Moskalenko OD, Kostromskoy FD, Ivankina EA, Dvorianinova EM, Krupskaya DA, Melnikova NV, Dmitriev AA.   +15 more
europepmc   +1 more source