Results 101 to 110 of about 1,502,773 (308)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Comparison of human (and other) genome browsers [PDF]

open access: yesHuman Genomics, 2006
The sequence of the human genome provides a scaffold on which numerous annotations, such the locations of genes, can be laid. Genome browsers have been created to allow the simultaneous display of multiple annotations within a graphical interface. In addition, they provide the ability to search for markers and sequences, to extract annotations for ...
openaire   +3 more sources

Intraspecies sequence comparisons for annotating genomes [PDF]

open access: yesGenome Research, 2004
Analysis of sequence variation among members of a single species offers a potential approach to identify functional DNA elements responsible for biological features unique to that species. Due to its high rate of allelic polymorphism and ease of genetic manipulability, we chose the sea squirt, Ciona intestinalis
Boffelli, Dario   +7 more
openaire   +3 more sources

Comparative analysis of the complete mitogenomes of Camellia sinensis var. sinensis and C. sinensis var. assamica provide insights into evolution and phylogeny relationship

open access: yesFrontiers in Plant Science
IntroductionAmong cultivated tea plants (Camellia sinensis), only four mitogenomes for C. sinensis var. assamica (CSA) have been reported so far but none for C. sinensis var. sinensis (CSS).
Li Li   +8 more
doaj   +1 more source

Virulent Epidemic Pneumonia in Sheep Caused by the Human Pathogen Acinetobacter baumannii

open access: yesFrontiers in Microbiology, 2018
The human pathogen Acinetobacter baumannii has emerged as a frequent cause of hospital-acquired infections, but infection of animals has rarely been observed.
Bodo Linz   +10 more
doaj   +1 more source

Hidden breakpoints in genome alignments

open access: yes, 2012
During the course of evolution, an organism's genome can undergo changes that affect the large-scale structure of the genome. These changes include gene gain, loss, duplication, chromosome fusion, fission, and rearrangement.
A. Rambaut   +14 more
core   +1 more source

Exploring single-sample SNP and INDEL calling with whole-genome de novo assembly [PDF]

open access: yes, 2012
Motivation: Eugene Myers in his string graph paper (Myers, 2005) suggested that in a string graph or equivalently a unitig graph, any path spells a valid assembly.
Depristo   +15 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Genome-Scale Compositional Comparisons in Eukaryotes [PDF]

open access: yesGenome Research, 2001
We examined dinucleotide relative abundances and their biases in recent sequences of eukaryotic genomes and chromosomes, including human chromosomes 21 and 22, Saccharomyces cerevisiae, Arabidopsis thaliana, and Drosophila melanogaster. We found that dinucleotide relative abundances are remarkably constant across human chromosomes and within the DNA of
A J, Gentles, S, Karlin
openaire   +2 more sources

Extensive Structural Variations Between Mitochondrial Genomes of CMS and Normal Peppers (Capsicum Annuum L.) Revealed by Complete Nucleotide Sequencing [PDF]

open access: yes, 2014
Cytoplasmic male sterility (CMS) is an inability to produce functional pollen that is caused by mutation of the mitochondrial genome. Comparative analyses of mitochondrial genomes of lines with and without CMS in several species have revealed structural ...
Choi, Yoomi   +4 more
core   +2 more sources

Home - About - Disclaimer - Privacy