Results 271 to 280 of about 1,502,773 (308)

Orthologs, paralogs and genome comparisons

Current Opinion in Genetics & Development, 1999
During the past decade, ancient gene duplications were recognized as one of the main forces in the generation of diverse gene families and the creation of new functional capabilities. New tools developed to search data banks for homologous sequences, and an increased availability of reliable three-dimensional structural information led to the ...
J P, Gogarten, L, Olendzenski
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Hadoop-Based Genome Comparisons

2012 Second International Conference on Cloud and Green Computing, 2012
Due to the ever increasing amounts of data in application areas relevant both for business and research, the requirements for data handling have increased significantly over the last years, often exceeding the capabilities of standard software, which has been used in specific application areas.
Paul Heinzlreiter, Michael T. Krieger, Iris Leitner   +2 more
openaire   +1 more source

Finding anchors for genomic sequence comparison

Proceedings of the eighth annual international conference on Computational molecular biology - RECOMB '04, 2004
Recent sequencing of the human and other mammalian genomes has brought about the necessity to align them, to identify and characterize their commonalities and differences. Programs that align whole genomes generally use a seed-and-extend technique, starting from exact or near-exact matches and selecting a reliable subset of these, called anchors, and ...
Ross Lippert, Xiaoyue Zhao, Liliana Florea, Clark M. Mobarry, Sorin Istrail   +4 more
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Family-Free Genome Comparison

2017
The comparison of genome structures across distinct species offers valuable insights into the species' phylogeny, genome organization, and gene associations. In this chapter, we review the family-free genome comparison tool FFGC which provides several methods for gene order analyses that do not require prior knowledge of evolutionary relationships ...
Dörr, Daniel, Feijão, Pedro, Stoye, Jens, Setubal, João C., Stadler, Peter, Stoye, Jens   +5 more
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Genome Comparison of Bacterial Pathogens

2009
Bacterial pathogens are being sequenced at an increasing rate. To many microbiologists, it appears that there simply is not enough time to digest all the information suddenly available. In this chapter we present several tools for comparison of sequenced pathogenic genomes, and discuss differences between pathogens and non-pathogens.
T M, Wassenaar, J, Bohlin, T T, Binnewies, D W, Ussery   +3 more
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High Throughput Comparison of Prokaryotic Genomes

2008
This work handles the optimization of the grid computing performances for a data-intensive and high "throughput" comparison of protein sequences. We use the word "throughput" from the telecommunication science to mean the amount of concurrent independent jobs in grid.
Luciana Carota, Lisa Bartoli, Piero Fariselli, Pier Luigi Martelli, Ludovica Montanucci, Giorgio Pietro Maggi, Rita Casadio   +6 more
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Family-Free Genome Comparison

The comparison of large-scale genome structures across distinct species offers valuable insights into the species' phylogeny, genome organization, and gene associations. In this chapter, we review the family-free genome comparison tool FFGC that, relying on built-in interfaces with a sequence comparison tool (either BLAST+ or DIAMOND) and with an ILP ...
Dias Vieira Braga, Marília, Doerr, Daniel, Rubert, Diego P., Stoye, Jens, Setubal, João Carlos, Stadler, Peter F., Stoye, Jens   +6 more
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A comparison of the genome organization of capripoxvirus with that of the orthopoxviruses

Journal of Virology, 1989
Comprehensive comparisons of genome organizations for poxviruses of different genera have not previously been reported. Here we have made such a comparison by cross-hybridizing genome fragments from capripoxvirus KS-1 and vaccinia virus WR (VV).
P D, Gershon, D M, Ansell, D N, Black
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Genome-Scale Model Management and Comparison

2013
Spurred by recent innovations in genome sequencing, the reconstruction of genome-scale models has increased in recent years. Genome-scale models are now available for a wide range of organisms, and models have been successfully applied to a number of research topics including metabolic engineering, genome annotation, biofuel production, and ...
Stephan, Pabinger, Zlatko, Trajanoski
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GCVT — A Genome Comparison and Viewing Tool

2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE), 2012
This paper highlights the features of a simple Genome Comparison and Viewing Tool (GCVT) for comparing bacterial genomes based on their genes, products, GC counts and genome sizes. For selected features from the results of comparison, a facility to perform alignment using the Needleman-Wunsch, Smith — Waterman and ClustalW algorithms is also provided ...
Shakuntala Baichoo, Parinita Ujoodha, Yovish Bissessur   +2 more
openaire   +1 more source