Results 281 to 290 of about 1,502,773 (308)
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Comparison of functional annotation schemes for genomes
Functional & Integrative Genomics, 2000In this paper we survey a number of functional classification schemes applicable to genomes. We present the concepts of depth, breadth and resolution as descriptors of the schemes' scope and architecture and compare selected classifications according to these criteria.
S C, Rison, T C, Hodgman, J M, Thornton
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Recognition of regulatory sites by genomic comparison
Research in Microbiology, 1999Availability of complete bacterial genomes opens the way to the comparative approach to the recognition of transcription regulatory sites. Assumption of regulon conservation in conjunction with profile analysis provides two lines of independent evidence making it possible to make highly specific predictions.
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WebACT: An Online Genome Comparison Suite
2007Comparison of related genomes is an enormously powerful technique for explaining phenotypic differences and revealing recent evolutionary events. Genomes evolve through a host of mechanisms including long- and short-range intragenomic rearrangements, insertion of laterally acquired DNA, gene loss, and single-nucleotide polymorphisms.
James C, Abbott +2 more
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Step-by-Step Bacterial Genome Comparison
Thanks to advancements in genome sequencing and bioinformatics, thousands of bacterial genome sequences are available in public databases. This presents an opportunity to study bacterial diversity in unprecedented detail. This chapter describes a complete bioinformatics workflow for comparative genomics of bacterial genomes, including genome annotation,Dennis, Carhuaricra-Huaman +1 more
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Genome Update: proteome comparisons
Microbiology, 2005Tim T, Binnewies +3 more
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An uneven race: genome editing for parasitic worms
Nature Reviews Microbiology, 2021Geetha Sankaranarayanan +2 more
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Computational genomics: mapping, comparison, and annotation of genomes.
2000Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2000. ; Includes bibliographical references (leaves 180-191). ; The field of genomics provides many challenges to computer scientists and mathematicians. The area of computational genomics has been expanding recently, and the timely application
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Genome-wide association studies of drug response and toxicity: an opportunity for genome medicine
Nature Reviews Drug Discovery, 2016Kathleen M Giacomini +2 more
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Engineered materials for in vivo delivery of genome-editing machinery
Nature Reviews Materials, 2019Sheng Tong, Buhle Moyo, Ciarán M Lee
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