Results 191 to 200 of about 1,963,187 (422)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Hindi Visual Genome: A Dataset for Multimodal English-to-Hindi Machine Translation [PDF]

arXiv, 2019
Visual Genome is a dataset connecting structured image information with English language. We present ``Hindi Visual Genome'', a multimodal dataset consisting of text and images suitable for English-Hindi multimodal machine translation task and multimodal research.
arxiv  

Human Genome Evolution. Edited by M. Jackson, T. Strachan and G. Dover. BIOS Scientific Publishers, 1996. 306 + x pages. Price £60.00 ($120). ISBN 1 859960 95 2. [PDF]

, 1997
Adrian Bird
openalex   +1 more source

The commercialization of genome-editing technologies

Critical Reviews in Biotechnology, 2017
The emergence of new gene-editing technologies is profoundly transforming human therapeutics, agriculture, and industrial biotechnology. Advances in clustered regularly interspaced short palindromic repeats (CRISPR) have created a fertile environment for mass-scale manufacturing of cost-effective products ranging from basic research to translational ...
Emily Vallillo, Seok Hyun Yun, Katelyn N. Brinegar, Ali Khademhosseini, Ali K. Yetisen, Sun Choi, Guillermo U. Ruiz-Esparza, Anand M. Prabhakar   +7 more
openaire   +2 more sources

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Genoomwijziging bij de mens : een overzicht van ethische en maatschappelijke vragen [PDF]

, 2018
Making targeted changes to an organism’s DNA is becoming easier, cheaper and more efficient than ever before due to scientific developments in the field of genome editing.
Segers, Seppe
core  

Genetic Alternatives for Experimental Adaptation to Colistin in Three Pseudomonas aeruginosa Lineages

Antibiotics
Pseudomonas aeruginosa is characterized by a high adaptive potential, developing resistance in response to antimicrobial pressure. We employed a spatiotemporal evolution model to disclose the pathways of adaptation to colistin, a last-resort polymyxin ...
Igor Chebotar, Tatiana Savinova, Julia Bocharova, Dmitriy Korostin, Peter Evseev, Nikolay Mayanskiy   +5 more
doaj   +1 more source

Investigation of Gene Expression and DNA Methylation From Seven Different Brain Regions of a Crab-Eating Monkey as Determined by RNA-Seq and Whole-Genome Bisulfite Sequencing

Frontiers in Genetics, 2019
The crab-eating monkey is widely used in biomedical research for pharmacological experiments. Epigenetic regulation in the brain regions of primates involves complex patterns of DNA methylation.
Won-Jun Lim, Won-Jun Lim, Kyoung Hyoun Kim, Kyoung Hyoun Kim, Jae-Yoon Kim, Jae-Yoon Kim, Hee-Jin Kim, Mirang Kim, Jong-Lyul Park, Seokjoo Yoon, Jung-Hwa Oh, Jae-Woo Cho, Yong Sung Kim, Namshin Kim, Namshin Kim   +14 more
doaj   +1 more source

Exploration of RNA Editing and Design of Robust Genetic Algorithms [PDF]

arXiv, 2003
This paper presents our computational methodology using Genetic Algorithms (GA) for exploring the nature of RNA editing. These models are constructed using several genetic editing characteristics that are gleaned from the RNA editing system as observed in several organisms.
arxiv