Results 211 to 220 of about 622,112 (341)

Surface-Enhanced Raman Spectroscopy for Monitoring the Biochemical Changes Due to DNA Mutations Induced by CRISPR-Cas9 Genome Editing in the Aspergillus niger Fungus [PDF]

Muhammad Wasim, Usman Ghaffar, Muhammad Rizwan Javed, Haq Nawaz, Muhammad Irfan Majeed, Anam Ijaz, Sheeba Ishtiaq, Nimra Rehman, Rabeea Razaq, Sobia Younas, Aqsa Bano, Naeema Kanwal, Muhammad Imran   +12 more
openalex   +1 more source

Genome editing in mammalian cells using the CRISPR type I-D nuclease

, 2021
Keishi Osakabe, Naoki Wada, Emi Murakami, Naoyuki Miyashita, Yuriko Osakabe   +4 more
openalex   +1 more source

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

Search-and-remove genome editing allows selection of cells by DNA sequence. [PDF]

Nat Commun
Fast L, Omar M, Kanis P, Schaffer T, Chowdhury D, Rakava E, Pääbo S, Riesenberg S.   +7 more
europepmc   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Versatile genome editing using Type I-E CRISPR-Cas3 in rice. [PDF]

Plant Cell Physiol
Saika H, Hara N, Yasumoto S, Muranaka T, Yoshimi K, Mashimo T, Toki S.   +6 more
europepmc   +1 more source

Selection-free, high frequency genome editing by homologous recombination of human pluripotent stem cells using Cas9 RNP and AAV6 [PDF]

, 2018
Renata M. Martin, Kazuya Ikeda, Nobuko Uchida, Kyle Cromer, T. Nishimura, Daniel P. Dever, Joab Camarena, Rasmus O. Bak, Anders Laustsen, Martin R. Jakobsen, Volker Wiebking, Vittorio Sebastiano, Hiromitsu Nakauchi, Matthew H. Porteus   +13 more
openalex   +1 more source

Triazine‐Trione Thermosets with High Processability for Scaffold Applications in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Novel photo‐clickable triazine‐trione thermosets can be shaped and cured under mild conditions, including room and physiological temperatures. These materials are biocompatible and support osteogenic differentiation of bone marrow–derived mesenchymal stem cells on their surface.
Åshild Johansen, Shuntaro Yamada, Daniel J. Hutchinson, Mohammed A. Yassin, Samih Mohamed‐Ahmed, Cecilie Gjerde, Michael Malkoch, Kamal Mustafa   +7 more
wiley   +1 more source

CRISPR/Cas9-based programmable genome editing in chickens: concepts, applications and regulatory issues. [PDF]

Front Genome Ed
Kolluri G, Naim A, Kumar Kurva S, Tyagi JS, Ansari MM, Tomar S, Tiwari AK, Chouhan L.   +7 more
europepmc   +1 more source

Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair [PDF]

, 2019
Nidaa A. Ababneh, Jakub Scaber, Rowan Flynn, Andrew G. L. Douglas, Martin R. Turner, David Sims, Ruxandra Dafinca, Sally A. Cowley, Kevin Talbot   +8 more
openalex   +1 more source