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2017
Silkworm is a lepidopteran insect that has been used as a model for a wide variety of biological studies. The microinjection technique is available and it is possible to cause transgenesis as well as target gene disruption via the genome editing technique. TALEN-mediated knock-out is especially effective in this species.
Takuya, Tsubota, Hideki, Sezutsu
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Silkworm is a lepidopteran insect that has been used as a model for a wide variety of biological studies. The microinjection technique is available and it is possible to cause transgenesis as well as target gene disruption via the genome editing technique. TALEN-mediated knock-out is especially effective in this species.
Takuya, Tsubota, Hideki, Sezutsu
openaire +2 more sources
2019
Programmable nucleases like CRISPR/Cas9 enable to edit the mouse genome directly in the zygote. Several methods have been successfully used for this. Here we describe injection into one of the pronuclei of the zygote and electroporation of zygotes. Alternative methods will be mentioned.
Lisbeth Ahm, Hansen +1 more
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Programmable nucleases like CRISPR/Cas9 enable to edit the mouse genome directly in the zygote. Several methods have been successfully used for this. Here we describe injection into one of the pronuclei of the zygote and electroporation of zygotes. Alternative methods will be mentioned.
Lisbeth Ahm, Hansen +1 more
openaire +2 more sources
Regulate genome-edited products, not genome editing itself
Nature Biotechnology, 2016Dana Carroll +4 more
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Science, 2009
![Figure][1] CREDIT: ROBERT HAMMERSMITH The ciliate Oxytricha trifallax has an unusual genome with the coding regions of genes (the exons) scattered through the genome. The exons are then somehow knitted together following transcription prior to their translation into proteins.
openaire +1 more source
![Figure][1] CREDIT: ROBERT HAMMERSMITH The ciliate Oxytricha trifallax has an unusual genome with the coding regions of genes (the exons) scattered through the genome. The exons are then somehow knitted together following transcription prior to their translation into proteins.
openaire +1 more source
An uneven race: genome editing for parasitic worms
Nature Reviews Microbiology, 2021Geetha Sankaranarayanan +2 more
exaly
Therapeutic genome editing in cardiovascular diseases
Advanced Drug Delivery Reviews, 2021Masataka Nishiga, Lei S Qi, Wu Jc
exaly