Results 291 to 300 of about 622,112 (341)

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
wiley   +1 more source

Manipulation of 7‑Finger Zinc Finger Nuclease Increases the Efficiency of Genome Editing in Human Cells. [PDF]

ACS Bio Med Chem Au
Katayama S, Watanabe M, Nomura W, Yamamoto T.   +3 more
europepmc   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Advancing nutritional quality in oilseed crops through genome editing: a comprehensive review. [PDF]

GM Crops Food
Menelih A, Girma A, Aemiro A.
europepmc   +1 more source

Rewriting the script: gene therapy and genome editing for von Willebrand Disease. [PDF]

Front Genome Ed
Barraclough A, Bär I, van Duijl T, Fijnvandraat K, Eikenboom JCJ, Leebeek FWG, Bierings R, Voorberg J, Trasanidou D.   +8 more
europepmc   +1 more source

Development of the CRISPR/Cas9 system for genome editing in Riemerella anatipestifer. [PDF]

Poult Sci
Chang Y, Huang H, Zhao R, Diao L, Xiong W, Wan P.   +5 more
europepmc   +1 more source

A start codon-targeted genome editing strategy for generating hypomorphic mutants of lethal plant genes. [PDF]

Plant Biotechnol (Tokyo)
Yoshimura M, Mamiya T, Takahashi N, Ishida T.   +3 more
europepmc   +1 more source

AI-driven advances in plant biotechnology: sharpening the edge of plant tissue culture and genome editing. [PDF]

Front Plant Sci
Narra M, Ray A, Polley B, Yang H, Bhowmik PK.   +4 more
europepmc   +1 more source

Generation and ophthalmological characterization of oculocutaneous albinism type 1 pig models by selection-free genome editing. [PDF]

Sci Rep
Oh D, Seok C, Park HW, Park S, Lee J, Choi H, Jawad A, Ham J, Jang H, Lee SC, Oh BC, Moon C, Park KH, Hyun SH, Kim D.   +14 more
europepmc   +1 more source

The Patentability of the Crispr-Cas9 Genome Editing Tool

, 2017
Deborah Ku
openalex   +1 more source