Results 231 to 240 of about 3,929,879 (390)

Genome engineering and direct cloning of antibiotic gene clusters via phage ϕBT1 integrase-mediated site-specific recombination in Streptomyces [PDF]

, 2015
Deyao Du, Lu Wang, Yuqing Tian, Hao Liu, Huarong Tan, Guoqing Niu   +5 more
openalex   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Mammalian genome writing: Unlocking new length scales for genome engineering. [PDF]

Cell
Pinglay S, Atwater JT, Brosh R, Shendure J, Maurano MT, Boeke JD.   +5 more
europepmc   +1 more source

Efficient mouse genome engineering by CRISPR-EZ technology

, 2018
A Modzelewski, Sean Chen, Brandon Willis, K. C. Kent Lloyd, Joshua A. Wood, Lin He   +5 more
openalex   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

SETDB1/ATF7IP regulate the precise genome engineering of HUSH-regulated genes. [PDF]

Epigenetics Chromatin
Ruis BL, Ward H, Myers CL, Bielinsky AK, Hendrickson EA.   +4 more
europepmc   +1 more source

Comparison and optimization of ten phage encoded serine integrases for genome engineering in Saccharomyces cerevisiae [PDF]

, 2016
Zhengyao Xu, William R. Brown
openalex   +1 more source

CRISPR RNA-guided integrases for high-efficiency, multiplexed bacterial genome engineering

Nature Biotechnology, 2020
P. Vo, Carlotta Ronda, Sanne E. Klompe, Ethan E. Chen, Christopher Acree, Harris H. Wang, S. H. Sternberg   +6 more
semanticscholar   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Applications of multiplexed CRISPR-Cas for genome engineering. [PDF]

Exp Mol Med
Cheng H, Jeong E, Cho SW.
europepmc   +1 more source