Results 151 to 160 of about 105,282 (228)
Impacts of large herbivores on mycorrhizal fungal communities across the Arctic
Ecography, EarlyView.Mycorrhizal fungi play an integral role in nutrient and carbon cycling in soils, which may be especially important in the Arctic, one of the world's most soil carbon‐rich regions. Large mammalian herbivores can influence these fungi through their impacts on vegetation and soil conditions, however the strength and prevalence of these interactions in the
Cole G. Brachmann +25 more
wiley +1 more source
ESC Heart Failure, EarlyView.Abstract Aims Protein glycosylation regulated by glycosyltransferases is an important type of post‐translational modification. The role of the glycosyltransferase genes (GTGs) in heart failure (HF) remains unclear and requires further investigation.
Jiahe Wu +5 more
wiley +1 more source
Environmental and Molecular Mutagenesis, EarlyView.Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons +17 more
wiley +1 more source
Environmental and Molecular Mutagenesis, EarlyView.Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk +4 more
wiley +1 more source
Food Bioengineering, EarlyView.ABSTRACT Artificial intelligence (AI) has emerged as a paradigm‐shifting force in enzyme engineering, enabling data‐driven prediction of catalytic activity, stability, and substrate specificity. By integrating large‐scale datasets from structured databases (e.g., PDB, BRENDA) and high‐throughput experimentation (e.g., deep mutational scanning ...
Xiafeng Lu +11 more
wiley +1 more source
Food Frontiers, EarlyView.Native Bacillus spp. isolated from cocoa fermentations demonstrate cadmium resistance and removal capabilities. Through a multidisciplinary approach combining genomics, metagenomics, electron microscopy and functional assays, we identified promising strains for sustainable cadmium bioremediation, offering a natural strategy to improve cocoa safety and ...
Miguel Fernández‐Niño +10 more
wiley +1 more source
From Genomic Fossils to Functional Elements: The Evolving Story of Pseudogenes
Advanced Genetics, EarlyView.This review begins with an introduction, summarizing the research background in pseudogene studies. It then contains three aspects: identification of pseudogenes, detailing their classification and features in metazoan genomes; functional pseudogenes, introducing their reactivation and regulation mechanisms; and pseudogenes’ contribution to species ...
Mengyao Sun, Yanni Ma, Jia Yu
wiley +1 more source
Advances in Detecting RNA Modifications Using Direct RNA Nanopore Sequencing
Advanced Genetics, EarlyView.This review examines recent advances in Oxford Nanopore Technologies direct RNA sequencing, highlighting its expanding capacity to detect RNA modifications beyond m6A. It discusses computational frameworks and basecalling innovations that enable single‐nucleotide and single‐molecule resolution, explores co‐occurring modifications and their regulatory ...
Yaran Liu, Yang Li, Qiang Sun
wiley +1 more source
Grassland Research, EarlyView.MsALKBH2 is an mRNA m6A demethylase in alfalfa that is required for enhancing drought tolerance through decreasing ROS content. Abstract Background N6‐methyladenosine (m6A), the most prevalent mRNA modification in plants, plays a pivotal role in developmental processes and stress responses.
Xianglong Zhao +8 more
wiley +1 more source