Results 211 to 220 of about 72,600 (260)

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman, Mossammat Rima Akter, Nur Alam   +2 more
wiley   +1 more source

Genome mining for the discovery of peptide halogenases and their biochemical characterization. [PDF]

Methods Enzymol
Saha N, Agarwal V.
europepmc   +1 more source

Temporal genetic relationships between growth, development, and malting quality in winter barley (Hordeum vulgare) using aerial imagery

The Plant Phenome Journal, Volume 9, Issue 1, December 2026.
Abstract Grain characteristics are the cumulative product of growth and development throughout the growing season. In barley (Hordeum vulgare), these traits determine the grain's value for malting purposes. The ability to accurately predict the genetic merit for malting quality is of great interest for barley breeding programs. Same‐season selection on
Amelia Loeb, Felipe Sabadin, Alexis Perry, Harmonie Bettenhausen, Gina Brown‐Guedira, Jared Smith, Kimberly Howell, Jason Walling, Hannah Uhlmann, Wynse Brooks, Nicholas Santantonio   +10 more
wiley   +1 more source

Discovery and Biosynthesis of Nyuzenamides D and E by Genome Mining in <i>Streptomyces hygroscopicus</i>. [PDF]

ACS Omega
Lum KY, Kumar R, Yang Z, Souza LDO, Jarmusch SA, Moreira JMA, Morth JP, Ding L.   +7 more
europepmc   +1 more source

Genome Mining Reveals Pathways for Terpene Production in Aerobic Endospore-Forming Bacteria Isolated from Brazilian Soils. [PDF]

Microorganisms
Mesquita FA, Silva WMCD, Raiol T, Brigido MM, Almeida NF, Fuga B, Cavalcante DA, De-Souza MT.   +7 more
europepmc   +1 more source

Genome Mining and Heterologous Reconstitution of a PKS-NRPS Gene Cluster from Aspergillus flavipes LY1-5 Affords Structurally Novel Tetronates. [PDF]

J Fungi (Basel)
Dai Q, Li Y, Lv S, Zhao S, Han L, Xu J, Shuai H, Zhang Y, Yan F.   +8 more
europepmc   +1 more source

Genome Mining Reveals a Novel Nephthenol-Producing Diterpene Synthase from the Sandfly Lutzomyia Longipalpis. [PDF]

Chembiochem
Ducker C, McKeown C, Da Silva IFP, Souza IT, Pickett JA, Santana AEG, Oldham NJ.   +6 more
europepmc   +1 more source

Genome mining and characterization of a heme-dependent enzyme catalyzing intermolecular Nitrogen-Nitrogen bond formation in hydrazinosuccinic acid biosynthesis. [PDF]

Synth Syst Biotechnol
Shi J, Zhao Z, Yang J, Cheng Z, Li H, Liu Y, Zhao G, Wu M, Du YL.   +8 more
europepmc   +1 more source

Deep-Sea Genome Mining Reveals Cooperative ATP-Grasp Ligase-Directed Biosynthesis of Pentacyclic Myxomiditides with Potent Protease Inhibition. [PDF]

JACS Au
Li Y, Wang J, Zhang Z, Zhang Y, Müller R, Huo L.   +5 more
europepmc   +1 more source

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Mining microsatellites in eukaryotic genomes

Trends in Biotechnology, 2007
During recent decades, microsatellites have become the most popular source of genetic markers. More recently, the availability of enormous sequence data for a large number of eukaryotic genomes has accelerated research aimed at understanding the origin and functions of microsatellites and searching for new applications.
Prakash C, Sharma, Atul, Grover, Günter, Kahl   +2 more
openaire   +2 more sources