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Mining the Pseudomonas Genome

2014
Pseudomonas species were targeted early for genomic studies since they were noted for their diverse metabolic capacity, ability to inhabit a wide range of environments and hosts, and include notable human and agriculturally relevant pathogens. As more genomes are sequenced, the power of genome-scale analyses are increasing and a wide range of analyses ...
Geoffrey L, Winsor, Fiona S L, Brinkman
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Mining the genomes of exceptional responders

Nature Reviews Cancer, 2014
The National Cancer Institute of the United States recently announced a major new initiative in understanding the genomes or, more broadly, the molecular phenotypes of exceptional responders. What can we expect to learn from exceptional responders? What are the potential benefits, and how do we approach studying them?
Chang, David K.   +3 more
openaire   +5 more sources

MINING THE GENOME

Chemical & Engineering News Archive, 2002
Having tackled the human genome, Celera's Gene Myers is now advancing on proteins and drug development. This article discusses Myers' work on developing computational biology for the human genome project. The further development of computational biology for the pharmaceutical industry is also discussed.
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Mining information for functional genomics

IEEE Intelligent Systems, 2002
Bernardi, Ratsch, Kania. Saric and Rojas discuss interdisciplinary work as the key to functional genomics. Park discusses network biology (data mining of biological networks). Schatz discusses the construction of analysis environments beyond the genome and the Web.
L. Bernardi   +9 more
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Mining the Genome of Cryptosporidium

2021
Cryptosporidium is a protozoan parasite responsible for causing diarrhoeal disease in humans. Cryptosporidiosis is spread by contact with contaminated municipal water supplies or swimming pools, and can pose a serious health risk for individuals with weakened immune systems.
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Mining the genome for iron

Nature, 2000
The level of iron in our blood is controlled by tightly regulating the amount of iron that is absorbed through the gut wall. This is a two-step process — iron is taken up in cells called enterocytes that line the gut, and then exported from the enterocytes into the bloodstream.
Jerry Kaplan, James P. Kushner
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Mining proteases in the genome databases

Essays in Biochemistry, 2002
Protease data mining can take advantage both of the many specialist, Web-available databases that cover the genetic, protein and nucleic acid sequence information that is specific to a variety of organisms, and of a flexible, but defined, classification system. However, precomputed data, such as gene predictions, should be used with care.
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Mining the Mammalian Genome for Artiodactyl Systematics

Systematic Biology, 2001
A total of 7,806 nucleotide positions derived from one mitochondrial and eight nuclear DNA segments were used to provide a robust phylogeny for members of the order Artiodactyla. Twenty-four artiodactyl and two cetacean species were included, and the horse (order Perissodactyla) was used as the outgroup.
C A, Matthee   +3 more
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Mining the Genome for Drugs

Science, 1999
SCIENCE AND BUSINESSPartly because of its early association with The Institute for Genomic Research, a company started by researchers who had devised an efficient way of finding genes, Human Genome Sciences Inc. of Rockville, Maryland, has a leg up on other biotech companies in current efforts to use modern genomics to find and develop new protein ...
openaire   +1 more source

Mining genomes and ‘metagenomes’ for novel catalysts

Current Opinion in Biotechnology, 2005
Advances in the field of genomics and 'metagenomics' have dramatically revised our view of microbial biodiversity and its potential for biotechnological applications. Considering the estimation that >99% of microorganisms in most environments are not amenable to culturing, very little is known about their genomes, genes and encoded enzymatic activities.
Manuel, Ferrer   +2 more
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