Results 281 to 290 of about 1,743,586 (380)

Investigation of the Cross-talk Mechanism in Caco-2 Cells during Clostridium difficile Infection through Genetic-and-Epigenetic Interspecies Networks: Big Data Mining and Genome-Wide Identification [PDF]

, 2017
Chengwei Li, Ming-He Su, Bor‐Sen Chen
openalex   +1 more source

Methyltransferase Domain-Focused Genome Mining for Fungal Polyketide Synthases. [PDF]

Small Methods
Yan D, Matsuda Y.
europepmc   +1 more source

Identification by Genome Mining of a Type I Polyketide Gene Cluster from Streptomyces argillaceus Involved in the Biosynthesis of Pyridine and Piperidine Alkaloids Argimycins P [PDF]

, 2017
Suhui Ye, Brian Molloy, Alfredo F. Braña, Daniel Zabala, Carlos Olano, Jesús Cortés, Francisco Morís, José A. Salas, Cármen Méndez   +8 more
openalex   +1 more source

Genome mining approach reveals the CRISPR-Cas systems features and characteristics in Lactobacillus delbrueckii strains. [PDF]

Heliyon
Panahi B, Rostampour M, Ghaffari MR, Nami Y.   +3 more
europepmc   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Biodegradation of DDT using multi-species mixtures: From genome-mining prediction to practical assessment. [PDF]

Microb Biotechnol
Vu PH, Nguyen DH, Vu TS, Le AH, Tran TQT, Nguyen YT, Nguyen TTT, Mai LDT, Bui HVT, Tran HM, Nguyen HQ, Nguyen TKN, Truong BG, Tran HTT, Pham HT.   +14 more
europepmc   +1 more source

Proteome‐Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases

Advanced Genetics, EarlyView.
Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li, Nicolas De Jay, Shan‐Shan Zhang, Xin Fang, Supriya Sharma, Katrina A. Catalano, Venkatesh Sridharan, Zhaoqing Wang, Lei Zhao, Joseph D. Szustakowski, Ching‐Pin Chang, Joseph C. Maranville, Emily R. Holzinger, Erika M. Kvikstad   +13 more
wiley   +1 more source

Targeted Genome Mining Facilitates the Discovery of a Promiscuous, Hyperthermostable Amidase from Thermovenabulum Gondwanense with Notable Nylon-Degrading Capacity. [PDF]

Angew Chem Int Ed Engl
Hoffman ER, Rangaswamy AMM, Cleveland ME, Keillor JW, Howe GW.   +4 more
europepmc   +1 more source

Mining the hidden treasures from canid genomes [PDF]

, 2018
Fangqing Zhao
openalex   +1 more source

The X‐Linked Intellectual Disability Gene, ZDHHC9, Is Important for Oligodendrocyte Subtype Determination and Myelination

Glia, EarlyView.
Zdhhc9 ablation grossly changes gene expression and myelin protein levels in CNS WM. Zdhhc9 is important for the establishment of mature oligodendrocyte subtypes. Zdhhc9 is important for axon myelination and the maintenance of myelin integrity. ABSTRACT Two percent of patients with X‐linked intellectual disability (XLID) exhibit loss‐of‐function ...
Rocio B. White, Angela R. Wild, Timothy P. O'Leary, Andrew J. Thompson, Stephane Flibotte, Angie Peng, Jason C. Rogalski, Mila Mair, Neeki Derhami, Shernaz X. Bamji   +9 more
wiley   +1 more source