Results 171 to 180 of about 1,156,580 (337)

Dormice functional genome annotation project: the first insights on regulation of hibernation

, 2022
H Carey, T Matthew, L Sandra, F Hoelzl, K Vermillion, K Anderson, M Hampton, M Andrews, K Storey   +8 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Helminth genome analysis: the current status of the filarial and schistosome genome projects. Filarial Genome Project. Schistosome Genome Project.

Parasitology, 1999
Genome projects for the parasitic helminths Brugia malayi (a representative filarial nematode) and Schistosoma were initiated in 1995 by the World Health Organization with the ultimate objectives of identifying new vaccine candidates and drug targets and of developing low resolution genome maps. Because no genetic maps are available, and very few genes
S A, Williams, D A, Johnston
openaire   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

The Karnataka Individual Genome Project expands the human reference landscape to include South Asia. [PDF]

HGG Adv
Ganesh A, Mhatre A, Chindarkar Y, Goswami M, Mishra P, Sharma A, Kalpande M, Ravindran F, Srinivasan S, Choudhary B.   +9 more
europepmc   +1 more source

Psychological and behavioural impact of returning personal results from whole-genome sequencing: the HealthSeq project [PDF]

, 2017
Saskia C. Sanderson, Michael D. Linderman, Sabrina A. Suckiel, Randi E. Zinberg, Melissa Wasserstein, Andrew Kasarskis, George A. Díaz, Eric E. Schadt   +7 more
openalex   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

The Ecological Genome Project and the Promises of Ecogenomics for Society: Realising a Shared Vision as One Health. [PDF]

Bioethics
Capps B, Chadwick R, Joly Y, Lajaunie C, Hauptmannova I, Mackenzie S, Mulvihill JJ, Mumford E, Rasmussen SA, Sanghavi K, Thaldar DW, Yeates J, Quinzin MC, Lederman Z.   +13 more
europepmc   +1 more source

30-year journey from the start of the Human Genome Project to clinical application of genomics in psychiatry: are we there yet? [PDF]

, 2019
Nina Roth Mota, Barbara Franke
openalex   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source