Results 11 to 20 of about 1,073,692 (309)

The Feline Genome Project [PDF]

open access: yesAnnual Review of Genetics, 2002
▪ Abstract  The compilation of a dense gene map and eventually a whole genome sequence (WGS) of the domestic cat holds considerable value for human genome annotation, for veterinary medicine, and for insight into the evolution of genome organization among mammals.
O'Brien, Stephen J.   +3 more
openaire   +4 more sources

Importance of HBsAg recognition by HLA molecules as revealed by responsiveness to different hepatitis B vaccines

open access: yesScientific Reports, 2021
Hepatitis B (HB) vaccines (Heptavax-II and Bimmugen) designed based on HBV genotypes A and C are mainly used for vaccination against HB in Japan. To determine whether there are differences in the genetic background associated with vaccine responsiveness,
Nao Nishida   +23 more
doaj   +1 more source

Genome Projects and the Functional-Genomic Era [PDF]

open access: yesCombinatorial Chemistry & High Throughput Screening, 2005
The problems we face today in public health as a result of the -- fortunately -- increasing age of people and the requirements of developing countries create an urgent need for new and innovative approaches in medicine and in agronomics. Genomic and functional genomic approaches have a great potential to at least partially solve these problems in the ...
Sauer, S., Konthur, Z., Lehrach, H.
openaire   +4 more sources

Towards the Physical Map of the Trypanosoma cruzi Nuclear Genome: Construction of YAC and BAC Libraries of the Reference Clone T. cruzi CL-Brener [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz, 1997
Strategies to construct the physical map of the Trypanosoma cruzi nuclear genome have to capitalize on three main advantages of the parasite genome, namely (a) its small size, (b) the fact that all chromosomes can be defined, and many of them can be ...
I Ferrari   +31 more
doaj   +1 more source

Claspin-Dependent and -Independent Chk1 Activation by a Panel of Biological Stresses

open access: yesBiomolecules, 2023
Replication stress has been suggested to be an ultimate trigger of carcinogenesis. Oncogenic signal, such as overexpression of CyclinE, has been shown to induce replication stress. Here, we show that various biological stresses, including heat, oxidative
Hao-Wen Hsiao   +2 more
doaj   +1 more source

Genome-wide copy number variation analysis of hepatitis B infection in a Japanese population

open access: yesHuman Genome Variation, 2021
Hepatitis B: Gene copy numbers associated with risk of infection The risk of contracting the hepatitis B virus may be linked to the number of copies of certain genes in an individual’s genome.
Masataka Kikuchi   +7 more
doaj   +1 more source

Analysis of SARS-CoV-2 genomic epidemiology reveals disease transmission coupled to variant emergence and allelic variation

open access: yesScientific Reports, 2021
The spread of SARS-CoV-2 created a pandemic crisis with > 150,000 cumulative cases in > 65 countries within a few months. The reproductive number (R) is a metric to estimate the transmission of a pathogen during an outbreak.
D J Darwin R. Bandoy, Bart C. Weimer
doaj   +1 more source

Medaka genome project [PDF]

open access: yesBriefings in Functional Genomics and Proteomics, 2008
The medaka Oryzias latipes is a small egg-laying freshwater teleost, and has become an excellent model system for ecotoxicology, developmental genetics, genomics and evolutionary biology studies. A high-quality draft genome sequence (700 Mb) of the medaka inbred strain, Hd-rR, has now been completed. In this review, we present an overview of the medaka
Hiroyuki Takeda, Daisuke Kobayashi
openaire   +3 more sources

Analyses of publicly available Hungatella hathewayi genomes revealed genetic distances indicating they belong to more than one species

open access: yesVirulence, 2021
Hungatella hathewayi has been observed to be a member of the gut microbiome. Unfortunately, little is known about this organism in spite of being associated with human fatalities; it is important to understand virulence mechanisms and epidemiological ...
Laura E. Hernández-Juárez   +7 more
doaj   +1 more source

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