Results 61 to 70 of about 5,973,095 (357)

Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome

Nature Communications, 2018
Clinical oncology is rapidly adopting next-generation sequencing technology for nucleotide variant and indel detection. Here the authors present a three-platform approach (whole-genome, whole-exome, and whole-transcriptome) in pediatric patients for the ...
Michael Rusch, Joy Nakitandwe, Sheila Shurtleff, Scott Newman, Zhaojie Zhang, Michael N. Edmonson, Matthew Parker, Yuannian Jiao, Xiaotu Ma, Yanling Liu, Jiali Gu, Michael F. Walsh, Jared Becksfort, Andrew Thrasher, Yongjin Li, James McMurry, Erin Hedlund, Aman Patel, John Easton, Donald Yergeau, Bhavin Vadodaria, Ruth G. Tatevossian, Susana Raimondi, Dale Hedges, Xiang Chen, Kohei Hagiwara, Rose McGee, Giles W. Robinson, Jeffery M. Klco, Tanja A. Gruber, David W. Ellison, James R Downing, Jinghui Zhang   +32 more
doaj   +1 more source

Genomic Standards Consortium Projects [PDF]

Standards in Genomic Sciences, 2014
The Genomic Standards Consortium (GSC) is an open-membership community that was founded in 2005 to work towards the development, implementation and harmonization of standards in the field of genomics. Starting with the defined task of establishing a minimal set of descriptions the GSC has evolved into an active standards-setting body that currently has
J. Wim De Smet, Hans-Peter Klenk, Lynette Hirschman, Jack A. Gilbert, Jack A. Gilbert, Renzo Kottmann, Dawn Field, Peter Dawyndt, Gregory J Caporaso, Guy Cochrane, Linda A. Amaral-Zettler, Robert J. Robbins, Lynn M. Schriml, Folker Meyer, Folker Meyer, John Wooley, Ilene Karsch-Mizrachi, Pelin Yilmaz, Nikos C. Kyrpides, George M. Garrity, Susanna Sansone, Tatiana Tatusova, Peter Sterk, Neil M Davies, Neil M Davies, Frank Oliver Glöckner, Owen White, Norman Morrison, Dave Ussery, Inigo San Gil, James R. Cole, Rob Knight   +31 more
openaire   +7 more sources

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

eLife, 2013
Breast cancer genomes have revealed a novel form of mutation showers (kataegis) in which multiple same-strand substitutions at C:G pairs spaced one to several hundred nucleotides apart are clustered over kilobase-sized regions, often associated with ...
Benjamin JM Taylor, Serena Nik-Zainal, Yee Ling Wu, Lucy A Stebbings, Keiran Raine, Peter J Campbell, Cristina Rada, Michael R Stratton, Michael S Neuberger   +8 more
doaj   +1 more source

HLA-A*11:01:01:01, HLA-C*12:02:02:01-HLA-B*52:01:02:02, Age and Sex Are Associated With Severity of Japanese COVID-19 With Respiratory Failure

Frontiers in Immunology, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing coronavirus disease 2019 (COVID-19) was announced as an outbreak by the World Health Organization (WHO) in January 2020 and as a pandemic in March 2020.
Seik-Soon Khor, Yosuke Omae, Nao Nishida, Masaya Sugiyama, Noriko Kinoshita, Tetsuya Suzuki, Michiyo Suzuki, Satoshi Suzuki, Shinyu Izumi, Masayuki Hojo, Norio Ohmagari, Masashi Mizokami, Katsushi Tokunaga   +12 more
doaj   +1 more source

Complete genome sequence of Meiothermus silvanus type strain (VI-R2). [PDF]

, 2010
Meiothermus silvanus (Tenreiro et al. 1995) Nobre et al. 1996 belongs to a thermophilic genus whose members share relatively low degrees of 16S rRNA gene sequence similarity.
Bristow, James, Chang, Yun-Juan, Chen, Amy, Cheng, Jan-Fang, Copeland, Alex, Eisen, Jonathan A, Glavina Del Rio, Tijana, Goodwin, Lynne, Göker, Markus, Han, Cliff, Hauser, Loren, Hugenholtz, Philip, Ivanova, Natalia, Jeffries, Cynthia D, Klenk, Hans-Peter, Kyrpides, Nikos C, Land, Miriam, Lapidus, Alla, Liolios, Konstantinos, Lowry, Stephen, Lucas, Susan, Markowitz, Victor, Mavromatis, Konstantinos, Mikhailova, Natalia, Nolan, Matt, Palaniappan, Krishna, Pati, Amrita, Pitluck, Sam, Rohde, Manfred, Sikorski, Johannes, Tice, Hope, Tindall, Brian J, Woyke, Tanja   +32 more
core   +1 more source

The NBDC-DDBJ imputation server facilitates the use of controlled access reference panel datasets in Japan

Human Genome Variation, 2022
Accurate genotype imputation requires large-scale reference panel datasets. When conducting genotype imputation on the Japanese population, researchers can use such datasets under collaborative studies or controlled access conditions in public databases.
Tsuyoshi Hachiya, Manabu Ishii, Yosuke Kawai, Seik-Soon Khor, Minae Kawashima, Licht Toyo-Oka, Nobutaka Mitsuhashi, Asami Fukuda, Yuichi Kodama, Takatomo Fujisawa, Katsushi Tokunaga, Toshihisa Takagi   +11 more
doaj   +1 more source

A sampling strategy for genome sequencing the British terrestrial arthropod fauna

Wellcome Open Research, 2023
The Darwin Tree of Life (DToL) project aims to sequence and assemble high-quality genomes from all eukaryote species in Britain and Ireland, with the first phase of the project concentrating on family-level coverage plus species of particular ecological,
Liam M. Crowley, Heather Allen, I. Barnes, D. Boyes, G. Broad, C. Fletcher, P. Holland, Inez Januszczak, M. Lawniczak, O. Lewis, C. Macadam, Peter O. Mulhair, Lyndall Pereira da Conceicoa, B. Price, C. Raper, Olga Sivell, Laura Sivess   +16 more
semanticscholar   +1 more source

The Qatar genome project: translation of whole‐genome sequencing into clinical practice

International journal of clinical practice, 2016
Qatar Genome Project was launched in 2013 with the intent to sequence the genome of each Qatari citizen in an effort to protect Qataris from the high rate of indigenous genetic diseases by allowing the mapping of disease‐causing variants/rare variants ...
H. Zayed
semanticscholar   +1 more source

An An accurate molecular method to sex elephants using PCR amplification of Amelogenin gene

Pachyderm, 2020
The use of molecular methods to identify the sex of elephants from non-invasive samples is essential for studies of population dynamics and population genetics.
George Lohay
doaj   +1 more source

The Genome Project of Taenia solium [PDF]

International Journal of Infectious Diseases, 2006
We have constituted a consortium of key laboratories at the National Autonomous University of Mexico to carry out a genomic project for Taenia solium. This project will provide powerful resources for the study of taeniasis/cysticercosis, and, in conjunction with the Echinococcus granulosus and Echinococcus multilocularis genome project of expressed ...
Hugo, Aguilar-Díaz, Raúl J, Bobes, Julio C, Carrero, Rafael, Camacho-Carranza, Claudia, Cervantes, Miguel A, Cevallos, Guillermo, Dávila, Mauricio, Rodríguez-Dorantes, Galileo, Escobedo, José Luis, Fernández, Gladis, Fragoso, Paul, Gaytán, Alejandro, Garciarubio, Victor M, González, Lorena, González, Marco V, José, Lucía, Jiménez, Juan P, Laclette, Abraham, Landa, Carlos, Larralde, Jorge, Morales-Montor, Enrique, Morett, Pedro, Ostoa-Saloma, Edda, Sciutto, Rosa I, Santamaría, Xavier, Soberón, Patricia, de la Torre, Víctor, Valdés, Jorge, Yánez   +28 more
openaire   +3 more sources