Results 91 to 100 of about 1,107,385 (165)
Linkage of A-to-I RNA Editing in Metazoans and the Impact on Genome Evolution
The adenosine-to-inosine (A-to-I) RNA editomes have been systematically characterized in various metazoan species, and many editing sites were found in clusters.
Y. Duan +5 more
semanticscholar +1 more source
The genetic code relates nucleotide sequence to amino acid sequence and is shared across all organisms, with the rare exceptions of lineages in which one or a few codons have acquired novel assignments. Recoding of UGA from stop to tryptophan has evolved
McDonald Bradon R. +8 more
core +1 more source
Genesis of ancestral haplotypes: RNA modifications and reverse transcription–mediated polymorphisms
Understanding the genesis of the block haplotype structure of the genome is a major challenge. With the completion of the sequencing of the Human Genome and the initiation of the HapMap project the concept that the chromosomes of the mammalian genome are
Stewart, B.J. +8 more
core
Synthetic Genome Construction Techniques to Edit the Genetic Code of Escherichia coli
The expansion of the genetic code to allow for site-specific incorporation of non-standard amino acids (nsAAs) — proteogenic amino acids other than the 22 found across life — is an important step in the development of new experimental and industrial ...
Baas-Thomas, Maximilien Sinclair
core
Genome Calligrapher: A Web Tool for Refactoring Bacterial Genome Sequences for de Novo DNA Synthesis
Recent advances in synthetic biology have resulted in an increasing demand for the de novo synthesis of large-scale DNA constructs. Any process improvement that enables fast and cost-effective streamlining of digitized genetic information into fabricable
Matthias Christen (1363884) +2 more
core +1 more source
Genome-based peptide fingerprint scanning
We have implemented a method that identifies the genomic origins of sample proteins by scanning their peptide-mass fingerprint against the theoretical translation and proteolytic digest of an entire genome.
Giddings, M. C. +3 more
core +1 more source
Genome engineering technologies for programming and recoding organisms
A defining cellular engineering challenge is the development of high-throughput and automated methodologies for precise design and manipulation of genomes.
Isaacs, Farren
core
Codon pair bias (CPB), which has been observed in all organisms, is a neglected genomic phenomenon that substantially affects gene expression. CPB results from synonymous codons that are paired more or less frequently in ORFeomes regardless of codon bias.
Wang, Bingyin
core

