Results 91 to 100 of about 1,799,072 (348)

PacBio assembly of a Plasmodium knowlesi genome sequence with Hi-C correction and manual annotation of the SICAvar gene family. [PDF]

, 2018
Plasmodium knowlesi has risen in importance as a zoonotic parasite that has been causing regular episodes of malaria throughout South East Asia. The P. knowlesi genome sequence generated in 2008 highlighted and confirmed many similarities and differences
Ay, F, Batugedara, G, Chien, J-T, DeBARRY, JD, Galinski, MR, Geraldo, JA, Humphrey, J, Kissinger, JC, Lapp, SA, Le Roch, KG, MaHPIC consortium, Pakala, SB   +11 more
core  

Correlation Between GC-content and Palindromes in Randomly Generated Sequences and Viral Genomes [PDF]

arXiv, 2013
GC-content, the ratio of guanine and cytosine bases in an entire nucleotide sequence, and palindromic sequences are unique for every organism due to genomic evolution. The goals of our research was to establish a correlation between GC-content and palindromic densities in wild-type viral and randomly-generated genomes.
arxiv  

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Whole genome sequencing in pharmacogenomics [PDF]

Frontiers in Pharmacology, 2015
Pharmacogenomics aims to shed light on the role of genes and genomic variants in clinical treatment response. Although, several drug-gene relationships are characterized to date, many challenges still remain toward the application of pharmacogenomics in the clinic; clinical guidelines for pharmacogenomic testing are still in their infancy, whereas the ...
Theodora Katsila, George P. Patrinos
openaire   +4 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

The Genome Sequence DataBase (GSDB): meeting the challenge of genomic sequencing [PDF]

Nucleic Acids Research, 1996
The genome sequence database (GSDB) is a complete, publicly available relational database of DNA sequences and annotation maintained by the National Center for Genome Resources (NCGR) under a Cooperative Agreement with the US Department of Energy (DOE).
Jillian Burton, Carol Harger, Mo Manning, John Rohrlich, David Rider, Shelley March, Chris Fields, Alicia Power, John O'Neill, David Crowley, Emily Dickinson, Charles Troup, Rhonda Reinert, Gifford Keen, Jolene Schwertfeger, Mia McLeod, Ada Espinosa-Lujan, Linda Smyth, Ed Franks, Maria Pumilia, Nina Thayer   +20 more
openaire   +2 more sources

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

The genome sequence of Schizosaccharomyces pombe [PDF]

Nature, 2002
We have sequenced and annotated the genome of fission yeast (Schizosaccharomyces pombe), which contains the smallest number of protein-coding genes yet recorded for a eukaryote: 4,824. The centromeres are between 35 and 110 kilobases (kb) and contain related repeats including a highly conserved 1.8-kb element.
Francis Galibert, Ann Cronin, Geoffrey M. Hodgson, S. Holroyd, Cherryl Hunt, Judith A. Potashkin, Carol Churcher, Ester Rabbinowitsch, Guido Volckaert, S. Squares, M. Lyne, Todd M. Lowe, Andrés Garzón, Andrés Garzón, Richard Reinhardt, N. Peat, Matthew Jones, David W. Ussery, S. Gentles, L. Jones, P. Eger, Juan Jimenez, Juan Jimenez, Bart Barrell, David L. Saunders, K. Stevens, Valerie Lelaure, D. Niblett, Elizabeth J. Huckle, Edouard Cadieu, Kathy Seeger, F. del Rey, Jacqueline Hayles, Tracey Chillingworth, N. Hamlin, Paul Nurse, S. Walsh, P. Davis, E. Holzer, Stephen Baker, S. Muller-Auer, Adrian Tivey, D. Basham, Michael A. Rieger, M. Rochet, John Woodward, C. Gabel, B. Grymonprez, Thomas M. Pohl, S. M. Hurst, M. Fuchs, D. Moestl, Karen Moore, D. Brown, Stéphanie Mottier, Marie-Adèle Rajandream, Miguel del Nogal Sánchez, M. Lucas, Sarah E. Hunt, Wolfgang Zimmermann, S. Leather, C. Odell, W. R. McCombie, L. Cruzado, P. Mooney, Stéphane Dréano, G. Thode, H. Wedler, Ruth Taylor, G. V. Shpakovski, Mark Simmonds, J. Hidalgo, Andrew G. Fraser, Rachel Lyne, Kylie R. James, Kim Rutherford, S. Howarth, Alfred Beck, M. Schafer, R. Connor, H. Hilbert, Victor A. Tallada, Victor A. Tallada, Z. Xiang, Ian T. Paulsen, E. Vanstreels, I. Langer, Stephen J. Aves, A. Stewart, I. Weltjens, Claude Gaillardin, Rita Aert, John Armstrong, Theresa Feltwell, Arlette Goble, Karen Brooks, Sharon Moule, J. Benito, T. Warren, R. Gwilliam, T. Hornsby, C. Fritzc, Angel Domínguez, Sharen Bowman, S. McDonald, L. Cerrutti, Michael A. Quail, R. Wambutt, Rafael R. Daga, Rafael R. Daga, Mark O. Collins, Sergio Moreno, Susan L. Forsburg, D. Pearson, Jason Skelton, S. Whitehead, J. McLean, Johan Robben, Bénédicte Purnelle, Valerie Wood, Sarah Sharp, Susan O'Neil, Karen Oliver, André Goffeau, K. Taylor, Karen Mungall, R. Squares, José L. Revuelta, David Harris, Kay Jagels, Stéphanie Gloux, Hans Lehrach, J. Sgouros, Steve D.M. Brown, K. Borzym, Simon Rutter, Lee Murphy   +136 more
openaire   +5 more sources

Genome-wide sequence variations between wild and cultivated tomato species revisited by whole genome sequence mapping

BMC Genomics, 2017
Background Cultivated tomato (Solanum lycopersicum L.) is the second most important vegetable crop after potato and a member of thirteen interfertile species of Solanum genus.
Kamlesh Kumar Sahu, Debasis Chattopadhyay   +1 more
doaj   +1 more source

Genome sequence of Acetomicrobium hydrogeniformans OS1 [PDF]

, 2018
Acetomicrobium hydrogeniformans, an obligate anaerobe of the phylum Synergistetes, was isolated from oil production water. It has the unusual ability to produce almost 4 molecules H2/molecule glucose. The draft genome of A.
Cook, Lauren E, Gang, Spencer S, Gunsalus, Robert P, Ihlan, Alicia, Lobos, Elizabeth A, Maune, Matthew, McInerney, Michael J, Tanner, Ralph S, Weinstock, George   +8 more
core   +2 more sources