Results 91 to 100 of about 5,239,885 (381)

De novo assembly of the carrot mitochondrial genome using next generation sequencing of whole genomic DNA provides first evidence of DNA transfer into an angiosperm plastid genome

BMC Plant Biology, 2012
Background Sequence analysis of organelle genomes has revealed important aspects of plant cell evolution. The scope of this study was to develop an approach for de novo assembly of the carrot mitochondrial genome using next generation sequence data from ...
Iorizzo Massimo, Senalik Douglas, Szklarczyk Marek, Grzebelus Dariusz, Spooner David, Simon Philipp   +5 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Gene duplication and paleopolyploidy in soybean and the implications for whole genome sequencing

BMC Genomics, 2007
Background Soybean, Glycine max (L.) Merr., is a well documented paleopolyploid. What remains relatively under characterized is the level of sequence identity in retained homeologous regions of the genome.
Nelson Rex T, Roe Bruce A, O'Bleness Majesta, Yi Jing, Deshpande Shweta, Vasylenko-Sanders Iryna F, Schlueter Shannon D, Lin Jer-Young, Schlueter Jessica A, Scheffler Brian E, Jackson Scott A, Shoemaker Randy C   +11 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Genome sequence of carboxylesterase, carboxylase and xylose isomerase producing alkaliphilic haloarchaeon Haloterrigena turkmenica WANU15

Genomics Data, 2016
We report draft genome sequence of Haloterrigena turkmenica strain WANU15, isolated from Soda Lake. The draft genome size is 2,950,899 bp with a G + C content of 64% and contains 49 RNA sequence.
Samy Selim, Nashwa Hagagy
doaj   +1 more source

Genome evolution during bread wheat formation unveiled by the distribution dynamics of SSR sequences on chromosomes using FISH

BMC Genomics, 2021
Background During the bread wheat speciation by polyploidization, a series of genome rearrangement and sequence recombination occurred. Simple sequence repeat (SSR) sequences, predominately located in heterochromatic regions of chromosomes, are the ...
Yingxin Zhang, Chengming Fan, Yuhong Chen, Richard R.-C. Wang, Xiangqi Zhang, Fangpu Han, Zanmin Hu   +6 more
doaj   +1 more source

Genome Sequence of Galleria mellonella (Greater Wax Moth)

Genome Announcements, 2018
The larvae of the greater wax moth, Galleria mellonella, are pests of active beehives. In infection biology, these larvae are playing a more and more attractive role as an invertebrate host model.
Anna Lange, Sina Beier, D. Huson, R. Parusel, F. Iglauer, J. Frick   +5 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A Solvable Sequence Evolution Model and Genomic Correlations

, 2005
We study a minimal model for genome evolution whose elementary processes are single site mutation, duplication and deletion of sequence regions and insertion of random segments.
Michael Lässig, Peter F. Arndt, Philipp W. Messer, R. Durbin, R. Mansilla, R. V. Samonte, S. Karlin, W. Li, W. Li   +8 more
core   +1 more source

The Genome Sequence DataBase (GSDB): meeting the challenge of genomic sequencing [PDF]

Nucleic Acids Research, 1996
The genome sequence database (GSDB) is a complete, publicly available relational database of DNA sequences and annotation maintained by the National Center for Genome Resources (NCGR) under a Cooperative Agreement with the US Department of Energy (DOE).
Jillian Burton, Carol Harger, Mo Manning, John Rohrlich, David Rider, Shelley March, Chris Fields, Alicia Power, John O'Neill, David Crowley, Emily Dickinson, Charles Troup, Rhonda Reinert, Gifford Keen, Jolene Schwertfeger, Mia McLeod, Ada Espinosa-Lujan, Linda Smyth, Ed Franks, Maria Pumilia, Nina Thayer   +20 more
openaire   +2 more sources