Results 101 to 110 of about 3,470,657 (312)

Predicting the virulence of MRSA from its genome sequence [PDF]

, 2014
This work is supported by the EC-FP7 program no. 245500 and the BBSRCMicrobial virulence is a complex and often multifactorial phenotype, intricately linked to a pathogen's evolutionary trajectory.
Josefsson, Elisabet,, Hawkins, E., Josefsson, Elisabet, Holden, M., Yajjala, Vijaya Kumar, Feil, E. J., Read, T. D., Recker, Mario, Rudkin, Justine K., P. D. Fey, Z. Gulay, Kumar Yajjala, Vijaya, Wilson, D., E. J. Feil, Williams, P., T. Widhelm, Sloan, Tim J, Fey, P. D., Gulay, Zeynep, Parfett, S., Gulay, Z., Endres, Jennifer L, M. Recker, Priest, Nicholas K, Hurst, Laurence D, E. Josefsson, Lewis, K., Fey, Paul D, Sloan, Tim J., van den Elsen, J., M. Laabei, Peacock, Sharon J., Priest, Nicholas K., Feil, Edward J., Read, Timothy D., Aldeljawi, Mona, Parfett, Sara, J. K. Rudkin, L. Scowen, Hurst, Laurence D., P. Williams, Widhelm, Todd, S. Parfett, J. L. Endres, N. K. Priest, S. J. Peacock, Massey, R. C., Holden, Matthew, Peacock, Sharon J, J. van den Elsen, Bayles, Kenneth W., M. Holden, Massey, Ruth C., Scowen, L., Feil, Edward J, Rudkin, J. K., Hurst, L. D., E. Hawkins, M. Aldeljawi, Rudkin, Justine K, Read, Timothy D, K. W. Bayles, V. K. Yajjala, Wilson, Daniel, T. J. Sloan, L. D. Hurst, Recker, M., Aldeljawi, M., D. Wilson, Bayles, K. W., Laabei, Maisem, K. Lewis, Bayles, Kenneth W, Scowen, Lucy, Endres, J. L., Laabei, M., Hawkins, Erica, Yajjala, V. K., Williams, Paul, Sloan, T. J., Massey, Ruth C, Lewis, Katie, Endres, Jennifer L., Fey, Paul D., Peacock, S. J., Priest, N. K., van den Elsen, Jean, R. C. Massey, T. D. Read, Widhelm, T., Holden, Matthew; id_orcid   +90 more
core   +1 more source

Whole genome sequence data of thermotolerant

Data in Brief
The whole genome sequence data of a thermotolerant bacterium, Pseudobacillus badius strain WCB-1, isolated from acidic hot spring sediment at Kawah Putih, West Java, Indonesia. The isolate was obtained using culture-based methods and initially identified
Alam Ahmad Hidayat, Digdo Sudigyo, Rudi Nirwantono, Joko Pebrianto Trinugroho, Fina Amreta Laksmi, Isa Nuryana   +5 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Insights into the Musa genome: Syntenic relationships to rice and between Musa species [PDF]

, 2008
Background Musa species (Zingiberaceae, Zingiberales) including bananas and plantains are collectively the fourth most important crop in developing countries.
Santos, Candice M.R., Sasaki Takuji, Magali Lescot, Matsumoto Takashi, D'Hont Angélique, Erin Hine, Pappas Junior, Georgios, Ciampi, A.Y., Pietro Piffanelli, D'Hont, Angélique, Althoff, Ryan, Manoel T Souza, Lescot Magali, Piffanelli, Pietro, Catherine M Ronning, Leebens-Mack Jim, Souza, M.T., Leebens-Mack, Jim, Ana Y Ciampi, Candice M.R Santos, Vilarinhos, Alberto, Ronning Catherine M, Manuel Ruiz, Vilarinhos Alberto D, Town Christopher D, Ciampi Ana Y, Ronning, Catherine, Santos, Candice Mr, Kanamori Hiroyuki, Ruiz, Manuel, Jim Leebens-Mack, Pappas Georgios J, Vilarinhos, Alberto Duarte, Arbogast, Tammy, Foo Cheung, Cheung, Foo, Ruiz Manuel, Lescot, Magali, Da Silva, Felipe, Town, Christopher, da Silva Felipe R, Matsumoto, Takashi, Haas, Brian, Miller, Robert Ng, Blanc Guillaume, Miller, Roberto Neil Gerard, Takashi Matsumoto, Souza, Manoel, Felipe R da Silva, Guillaume Blanc, Arbogast Tammy, Haas Brian J, Miller Robert NG, Takuji Sasaki, Chris D Town, Garsmeur, Olivier, Piffanelli Pietro, Hiroyuki Kanamori, Robert N. G. Miller, Alberto D Vilarinhos, Ciampi, Ana, Tammy Arbogast, Santos Candice MR, Santos, C.R., Althoff Ryan, Vilarinhos, A., Milller, R.N.G., Sasaki, Takuji, Garsmeur Olivier, Blanc, Guillaume, Angelique D'Hont, Pappas, Georgios, Glaszmann Jean-Christophe, Kanamori, Hiroyuki, Olivier Garsmeur, Souza Manoel T, Pappas, G., Ryan Althoff, Cheung Foo, Piffanelli, P., Dhont, A., Georgios J Pappas, Hine, Erin, Jean-Christophe Glaszmann, Glaszmann, Jean-Christophe, Silva, F.R., Brian J Haas, Hine Erin   +87 more
core   +1 more source

Genome sequencing and cancer [PDF]

Current Opinion in Genetics & Development, 2012
New technologies for DNA sequencing, coupled with advanced analytical approaches, are now providing unprecedented speed and precision in decoding human genomes. This combination of technology and analysis, when applied to the study of cancer genomes, is revealing specific and novel information about the fundamental genetic mechanisms that underlie ...
openaire   +2 more sources

Chloroplast genome sequence of the wild tetraploid potato relative Solanum stoloniferum

Mitochondrial DNA. Part B. Resources, 2018
Solanum stoloniferum is a wild tuber-bearing species belonging to Solanaceae family. The complete chloroplast genome of S. stoloniferum was constituted by de novo assembly using a small amount of whole genome sequencing data. The chloroplast genome of S.
Tae-Ho Park
doaj   +1 more source

Genome-Tools: A Flexible Package for Genome Sequence Analysis

BioTechniques, 2002
Genome-tools is a Perl module, a set of programs, and a user interface that facilitates access to genome sequence information. The package is flexible, extensible, and designed to be accessible and useful to both nonprogrammers and programmers.
William Lee, Swaine L. Chen
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

De novo assembly of the carrot mitochondrial genome using next generation sequencing of whole genomic DNA provides first evidence of DNA transfer into an angiosperm plastid genome

BMC Plant Biology, 2012
Background Sequence analysis of organelle genomes has revealed important aspects of plant cell evolution. The scope of this study was to develop an approach for de novo assembly of the carrot mitochondrial genome using next generation sequence data from ...
Iorizzo Massimo, Senalik Douglas, Szklarczyk Marek, Grzebelus Dariusz, Spooner David, Simon Philipp   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source