Results 141 to 150 of about 892,241 (298)
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
GMOL: An Interactive Tool for 3D Genome Structure Visualization [PDF]
arXiv, 2015 It has been shown that genome spatial structures largely affect both genome activity and DNA function. Knowing this, many researchers are currently attempting to accurately model genome structures. Despite these increased efforts there still exists a shortage of tools dedicated to visualizing the genome.
arxiv
Genome sequence data of Bacillus amyloliquefaciens L-17
Data in Brief, 2021 Bacillus amyloliquefaciens L-17 strain was isolated from a sample of chicken feathers. Here, we report complete genome sequence data of B. amyloliquefaciens L-17. The size of the genome is 3,933,788 bp which harbours 4001 coding Sequences. The BioProject
Meriem Zaidi-Ait Salem +2 more
doaj
Nucleotide sequence analysis of two simian virus 40 mutants with deletions in the late region of the genome [PDF]
, 1979 Roland Contreras +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Random Fragments Classification of Microbial Marker Clades with Multi-class SVM and N-Best Algorithm [PDF]
arXiv, 2019 Microbial clades modeling is a challenging problem in biology based on microarray genome sequences, especially in new species gene isolates discovery and category. Marker family genome sequences play important roles in describing specific microbial clades within species, a framework of support vector machine (SVM) based microbial species classification
arxiv
Rous sarcoma virus genome is terminally redundant: the 3' sequence. [PDF]
, 1977 Dennis Schwartz +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source