Results 181 to 190 of about 1,118,249 (314)

Clinical application of whole exome and genome sequencing in pediatric neurodevelopmental disorders. [PDF]

Clin Exp Pediatr
Lee KS, Oh SH, Lee JY, Seo GH, Roh DE, Park JK, Lee BL.   +6 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Clinical utility of 'Shaken' biopsies for whole-genome sequencing. [PDF]

J Clin Pathol
Nelan R, Mijuskovic M, Hughes M, Becq J, Kingsbury Z, Tsogka E, He M, Vucenovic D, Craig C, Elgar G, Levey P, Suaris T, Walsh E, Ross M, Jones JL.   +14 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Sequencing of Genomic DNA [PDF]

BioTechniques, 1999
Ulrich Mahlknecht, Dieter Hoelzer, Richard Bucala   +2 more
openaire   +3 more sources

Complete genome sequencing and evolutionary analyses of duck hepatitis a viruses in Egyptian duck farms. [PDF]

BMC Vet Res
Yehia N, AbdelSabour MA, Said D, El Naggar RF, Madbouly YM, Mohamed AAE, Salaheldin AH, Rohaim MA.   +7 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Draft genome sequencing of a <i>Staphylococcus aureus</i> clinical isolate from an inflamed wound. [PDF]

Microbiol Resour Announc
Ahmed IA, Thabit ZA, Ghayyib AA, Mamoori YI, Jaafer MR, Hasan NS.   +5 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Case Report: Whole genome sequencing of small cell ovarian carcinomas. [PDF]

Front Oncol
Daoud S, Tinsley E, Treacy A, Miller C, Thompson C, Hennessey BT, Toomey S, Furney SJ.   +7 more
europepmc   +1 more source