Results 91 to 100 of about 1,526,357 (323)

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source

Molecular cytogenetics of Dictyoloma vandellianum A. Juss. and the ancestral karyotype of Rutaceae

Acta Botânica Brasílica, 2022
Determination of the chromosome base number of a taxon is fundamental to understanding karyotypic variation and its implications for the evolution of that group.
Amanda Santos, Ana Emília Barros e Silva, Milton Groppo, Marcelo Guerra   +3 more
doaj   +1 more source

Evolution of genome size in asexual populations

, 2015
Genome sizes have evolved to vary widely, from 250 bases in viroids to 670 billion bases in amoeba. This remarkable variation in genome size is the outcome of complex interactions between various evolutionary factors such as point mutation rate ...
Adami, Christoph, Gupta, Aditi, LaBar, Thomas, Miyagi, Michael   +3 more
core   +1 more source

Complete genome sequences of escherichia coli phages vB_EcoM-EP75 and vB_EcoP-EP335 [PDF]

, 2019
Phages vB_EcoM-EP75 (EP75) and vB_EcoP-EP335 (EP335) specifically infect Shiga toxin (Stx)-producing Escherichia coli (STEC) O157 strains. EP75 has a genome size of 158,143 bp and belongs to the genus Vi1virus The genome size of EP335 is 76,622 bp, and ...
Fieseler, Lars, Hagens, Steven, Klamert, Silvia, van de Straat, Leoni, van Mierlo, Joël, Witte, Sander   +5 more
core   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

On the Relationship between Pollen Size and Genome Size [PDF]

Journal of Botany, 2010
Here we test whether genome size is a predictor of pollen size. If it were, inferences of ancient genome size would be possible using the abundant paleo-palynolgical record. We performed regression analyses across 464 species of pollen width and genome size. We found a significant positive trend.
Knight, Charles A., Clancy, Rachel B., Götzenberger, Lars, Dann, Leighton, Beaulieu, Jeremy M.   +4 more
openaire   +3 more sources

The dynamics of genome size and GC contents evolution in genus Nicotiana

Brazilian Journal of Biology, 2021
Hybridization and Polyploidization are most common of the phenomenon observed in plants, especially in the genus Nicotiana leading to the duplication of genome.
Z. Hussain, Y. Sun, S. H. Shah, H. Khan, S. Ali, A. Iqbal, M. A. Zia, S. S. Ali   +7 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Spontaneous mutation accumulation in multiple strains of the green alga, Chlamydomonas reinhardtii [PDF]

, 2014
Estimates of mutational parameters, such as the average fitness effect of a new mutation and the rate at which new genetic variation for fitness is created by mutation, are important for the understanding of many biological processes. However, the causes
Adams, Baer, Baer, Baranyi, Barrick, Bateman, Charlesworth, Charlesworth, Crutchfield, Davies, Dickinson, Drake, Fernandez, Fisher, Fry, García-Dorado, Goffeau, Goho, Gong, Haerty, Halligan, Halligan, Hartfield, Joseph, Keightley, Keightley, Keightley, Keightley, Keightley, Keightley, Kibota, Knight, Kondrashov, Koonin, Liss, Loewe, Lukjancenko, Lynch, Lynch, Lynch, Lynch, Massey, Matic, Merchant, Mukai, Mukai, Ness, Otto, R Core Team, Schaack, Schoen, Schrider, Schultz, Sharp, Shaw, Smith, Sokal, Sousa, Sundin, Sung, The Arabadopsis, The C. elegans Sequencing Consortium, Torgerson, Winzeler, Zeyl, Zuur   +65 more
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source