Results 251 to 260 of about 4,923,579 (336)

Correction to "Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability". [PDF]

Nucleic Acids Res
europepmc   +1 more source

HELQ Maintains Genome Stability of Primordial Germ Cells by Inhibiting LINE-1 Expression. [PDF]

FASEB J
Cao L, Ren J, Kong Z, Hu M, Zhang Y, Chen ZJ, Qin Y, Yang Y, Zhao S.   +8 more
europepmc   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Claudin-4 as a dual regulator of genome stability and immune evasion in high grade serous ovarian cancer. [PDF]

Sci Rep
Bitler BG, Lang J, Nunez-Avellaneda D, Behbakht K, Davidson NR, Woodruff ER, Villagomez FR.   +6 more
europepmc   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Transcription-Coupled Repair and R-Loop Crosstalk in Genome Stability. [PDF]

Int J Mol Sci
Jeon J, Kang TH.
europepmc   +1 more source

Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias

Nature Metabolism, 2019
R. Hämäläinen, R. Hämäläinen, J. Landoni, K. Ahlqvist, S. Goffart, Sanna Ryytty, M. O. Rahman, Virginia Brilhante, Katherine Icay, S. Hautaniemi, Liya Wang, M. Laiho, A. Suomalainen   +12 more
semanticscholar   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

AtCHE1, the Arabidopsis homolog of mammalian AATF/Che-1 protein, is involved in safeguarding genome stability. [PDF]

Commun Biol
Liu F, Wang B, Wang X, Dong D, De Veylder L, Qi S, Horvath BM, Palme K, Li X.   +8 more
europepmc   +1 more source

Functional interaction between the DNA damage tolerance pathway and the DNA damage checkpoint : implications for genome stability and oncogenesis

, 2016
Chames Kermi
openalex   +1 more source