Results 161 to 170 of about 1,470,585 (295)

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

The complete mitochondrial genome of Sindiplozoon coreius: genome structure description, comparative analysis, and phylogenetic implications. [PDF]

BMC Genomics
Shen L, Fan LX, Meng FY.
europepmc   +1 more source

Three-dimensional genome structure and function. [PDF]

MedComm (2020), 2023
Liu H, Tsai H, Yang M, Li G, Bian Q, Ding G, Wu D, Dai J.   +7 more
europepmc   +1 more source

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

A diverse satellite DNA repertoire in <i>Limnoperna fortunei</i>: insights into genome structure and chromosomal organization. [PDF]

Front Mol Biosci
Castro JP, Degrandi TM, Leal AO, Ferreira Júnior AL, de Almeida MC, Artoni RF.   +5 more
europepmc   +1 more source

Structural Genomics [PDF]

, 2020
openaire   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Conservation of giant genome structure in Brazilian and Chilean species of the genus Alstroemeria L. (Alstroemeriaceae), despite dynamism in satellite repeats. [PDF]

Planta
Nascimento J, Sader M, Toro-Núñez O, Baeza C, Mata-Sucre Y, Félix L, Pedrosa-Harand A.   +6 more
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Meiotic cohesin RAD21L shapes 3D genome structure and transcription in the male germline. [PDF]

Sci Adv
Marín-Gual L, Vara C, Sainz-Urruela R, Cuartero Y, Álvarez-González L, Felipe-Medina N, Garcia F, Llano E, Marti-Renom MA, Pendás AM, Ruiz-Herrera A.   +10 more
europepmc   +1 more source