Results 161 to 170 of about 8,437,199 (261)

Conservation of bilaterian genome structure is the exception, not the rule. [PDF]

Genome Biol
Lewin TD, Liao IJ, Luo YJ.
europepmc   +1 more source

Three-dimensional genome structure and function. [PDF]

MedComm (2020), 2023
Liu H, Tsai H, Yang M, Li G, Bian Q, Ding G, Wu D, Dai J.   +7 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Genomic characterization of clinical Helicobacter pylori strains from Korea: insights into phylogeny, pan-genome structure, and virulence factors. [PDF]

BMC Microbiol
Jung HE, Bang CS, Ahn JY, Jung HY, Lee SM, Kim SW, Chae DW, Gong EJ.   +7 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Pervasive genome structure heterogeneity in <i>Mycobacterium tuberculosis</i> constitutively generates subpopulations with distinct clinical phenotypes. [PDF]

iScience
Modlin SJ, Robinhold C, Elghraoui A, Valafar F.   +3 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

The complete mitochondrial genome of Sindiplozoon coreius: genome structure description, comparative analysis, and phylogenetic implications. [PDF]

BMC Genomics
Shen L, Fan LX, Meng FY.
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

A diverse satellite DNA repertoire in <i>Limnoperna fortunei</i>: insights into genome structure and chromosomal organization. [PDF]

Front Mol Biosci
Castro JP, Degrandi TM, Leal AO, Ferreira Júnior AL, de Almeida MC, Artoni RF.   +5 more
europepmc   +1 more source