Results 261 to 270 of about 1,470,585 (295)
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Genome structure of spirochetes

Research in Microbiology, 1992
The genome structures of several pathogenic spirochetes have recently been determined. The genomes of Borrelia species consist of a linear chromosome of approximately one million base pairs (Mb) and various linear and circular plasmids. Analysis of restriction fragment length polymorphisms and 16S ribosomal RNA sequence data indicate the division of ...
I, Saint Girons   +5 more
openaire   +2 more sources

Structural genomics of GPCRs

Trends in Biotechnology, 2005
G protein-coupled receptors (GPCRs) are targets for 60-70% of drugs in development today. Traditionally, the drug discovery process has relied on screening of chemical compounds to identify novel and more-efficient drug molecules. Structure-based drug design, however, provides a targeted approach but has been severely hampered by limited knowledge of ...
openaire   +2 more sources

Genome Structure and Comparative Genomics

2016
Two genome assemblies have been generated for Setaria italica, one in the accession Yugu1 and one in the accession Zhang gu. A comparison of the two assemblies showed overall high levels of colinearity, but identified a number of likely misoriented and/or misplaced sequence scaffolds.
Katrien M. Devos, Xiaomei Wu, Peng Qi
openaire   +1 more source

Cancer epigenetics in clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Veronica Davalos, Manel Esteller
exaly  

Structural Genomics

2008
John B. Heppner   +104 more
  +4 more sources

Structural Genomics

2013
M.-A. Elsliger, I.A. Wilson
openaire   +2 more sources

Computational methods for analysing multiscale 3D genome organization

Nature Reviews Genetics, 2023
Yang Zhang   +2 more
exaly  

The relationship between genome structure and function

Nature Reviews Genetics, 2020
Douglas Higgs, Douglas R Higgs
exaly  

In situ genome sequencing resolves DNA sequence and structure in intact biological samples

Science, 2021
Andrew C Payne   +2 more
exaly  

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