Genome-wide association study (GWAS) of leaf cuticular wax components in Camelina sativa identifies genetic loci related to intracellular wax transport. [PDF]
BMC Plant Biol, 2019 Luo Z +3 more
europepmc +1 more source
Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel +5 more
wiley +1 more source
Replication of genome-wide association study (GWAS) susceptibility loci in a Latino bipolar disorder cohort. [PDF]
Bipolar Disord, 2016 Gonzalez S +14 more
europepmc +1 more source
Exploring the genetic overlap between substance use disorder and educational attainment
Addiction, EarlyView.Abstract Background and aims Substance use disorder (SUD) is a polygenic psychiatric condition characterized by persistent drug use despite negative consequences. Several studies support that higher cognitive performance and educational attainment (EA) are associated with a reduced risk for SUD.
Judit Cabana‐Domínguez +16 more
wiley +1 more source
Exploring causal correlations between oily fish intake and multiple sclerosis: A two-sample Mendelian randomization study. [PDF]
Asia Pac J Clin NutrChang S, Shi K, Zhang M.
europepmc +1 more source
From SNPs to pathways: Biological interpretation of type 2 diabetes (T2DM) genome wide association study (GWAS) results. [PDF]
PLoS One, 2018 Cirillo E +8 more
europepmc +1 more source
Trajectories of genetic risk across dimensions of alcohol use behaviors
Addiction, EarlyView.Abstract Background and aims Alcohol use behaviors (AUBs) manifest in a variety of normative and problematic ways across the life course, all of which are heritable. Twin studies show that genetic influences on AUBs change across development, but this is usually not considered in research identifying and investigating the genes linked to AUBs ...
Jeanne E. Savage +127 more
wiley +1 more source
Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population. [PDF]
Nutrients, 2019 Coltell O +14 more
europepmc +1 more source
Addiction, EarlyView.Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova +2 more
wiley +1 more source
Genome-wide association study (GWAS) reveals the genetic architecture of four husk traits in maize. [PDF]
BMC Genomics, 2016 Cui Z +7 more
europepmc +1 more source