Results 261 to 270 of about 821,530 (308)

Isolation and genomic characterization of Chikungunya virus during the 2025 outbreak in Foshan, China. [PDF]

Emerg Microbes Infect
Sun C, Zhang L, Yi H, Wan S, Zhu A, Yuan B, Yan Q, Peng X, Yu C, Zhang X, Fu K, Zeng J, Shi Y, Huang L, Wang Y, Zhao J, Li B.   +16 more
europepmc   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

Synchronizing the Osteochondral Regeneration Process through Spatial Patterning of Stable and Hypertrophic Cartilage Organoids

Advanced Materials, EarlyView.
Zonated osteochondral assembloid implants are engineered through scaffold‐free spatial assembly of induced pluripotent stem cell (iPSC)‐derived chondrocyte organoids and periosteum‐derived osteogenic organoids. Implanted into full‐thickness rat osteochondral defects, they promote hyaline‐like cartilage repair, support subchondral bone formation with ...
Liuqi Peng, Isaak Decoene, Hanna Svitina, Ioannis Papantoniou   +3 more
wiley   +1 more source

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

Advanced Materials, EarlyView.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad, Verena J. Kast, Dagmar Pette, Franziska Baenke, Daniel E. Stange, Carsten Werner, Daniela Loessner   +6 more
wiley   +1 more source

A de Novo 2q23.1-2q23.3 duplication in a neonate with anemia, thrombocytopenia, and hypospadias: clinical and genomic characterization. [PDF]

Mol Cytogenet
Zhang B, Zhang C, Chen P, Hao R, An L.
europepmc   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Genomic Characterization of NDM-1 Producer <i>Providencia stuartii</i> Isolated in Russia. [PDF]

Antibiotics (Basel)
Shapovalova VV, Ageevets VA, Ageevets IV, Avdeeva AA, Sulian OS, Matsvay AD, Savochkina YA, Belyakova EN, Shipulin GA, Sidorenko SV.   +9 more
europepmc   +1 more source

Genomic characterization of host gene alterations in Theileria annulata-transformed leukocytes. [PDF]

Commun Biol
Dandasena D, Suresh A, Budhwar R, Godwin J, Singh S, Subudhi M, A VM, T A, Roy S, Bhandari V, Sharma P.   +10 more
europepmc   +1 more source

Genomic characterization of multidrug-resistant Klebsiella pneumoniae from an outbreak in Northeastern Brazil: mechanisms of virulence and resistance. [PDF]

Braz J Microbiol
Rosa DS, de Lima GBV, Vieira HDS, Aburjaile FF, Azevedo VAC, Brenig B, da Costa MM.   +6 more
europepmc   +1 more source