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Genomic characterization of metastatic breast cancers

Nature, 2019
Metastasis is the main cause of death for patients with breast cancer. Many studies have characterized the genomic landscape of breast cancer during its early stages. However, there is evidence that genomic alterations are acquired during the evolution of cancers from their early to late stages, and that the genomic landscape of early cancers is not ...
François Bertucci   +2 more
exaly   +4 more sources

Characterizing the physical genome

Nature Genetics, 2002
The genome of an organism is a dynamic physical entity, comprising genomic DNA bound to many different proteins and organized into chromosomes. A thorough characterization of the physical genome is relevant to our understanding of processes such as the regulation of gene expression, DNA replication and repair, recombination, chromosome segregation ...
Jonathan R, Pollack, Vishwanath R, Iyer
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Characterization of Allomyces genome

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1977
Allomyces arbuscula DNA isolated from whole cells (bulk DNA) is composed of a major (alpha) and two minor components (beta & gamma) with buoyant densities in neutral CsCl corresponding to 1.721, 1.710 and 1.702 g/cm3, respectively. The DNA obtained from purified nuclei contains alpha component only.
M, Ojha, H, Turler, G, Turian
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